DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42741 and KLF17

DIOPT Version :9

Sequence 1:NP_611747.2 Gene:CG42741 / 37654 FlyBaseID:FBgn0261705 Length:362 Species:Drosophila melanogaster
Sequence 2:NP_775755.3 Gene:KLF17 / 128209 HGNCID:18830 Length:389 Species:Homo sapiens


Alignment Length:345 Identity:81/345 - (23%)
Similarity:116/345 - (33%) Gaps:128/345 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly   140 EDNNNSCSYNNGSSSGGAGSAANS-------------------------------MQDYESKFSL 173
            :||.||....|.|||.|:.....|                               :.:...:||:
Human    27 QDNENSAPILNMSSSSGSSGVHTSWNQGLPSIQHFPHSAEMLGSPLVSVEAPGQNVNEGGPQFSM 91

  Fly   174 --------------------------------LSLFKNPYKFAGGDGQASRKTSPTGGSSK---- 202
                                            :::|..|.....|:....|...|.||:.:    
Human    92 PLPERGMSYCPQATLTPSRMIYCQRMSPPQQEMTIFSGPQLMPVGEPNIPRVARPFGGNLRMPPN 156

  Fly   203 ----------PLASNSS------------PSWKSYAGSGSPHAALNPAFGGMGR----------G 235
                      |:.|::.            ||.::..|...|..........|.:          |
Human   157 GLPVSASTGIPIMSHTGNPPVPYPGLSTVPSDETLLGPTVPSTEAQAVLPSMAQMLPPQDAHDLG 221

  Fly   236 ATRKDNSSFSGINFGGGGSAFGFTTSSDSMANGGY---------NDLSKNRKVHK---------- 281
            ....::.|...:     ||.....:..||. .|.:         ..:.||.:..:          
Human   222 MPPAESQSLLVL-----GSQDSLVSQPDSQ-EGPFLPEQPGPAPQTVEKNSRPQEGTGRRGSSEA 280

  Fly   282 ----CDTEGCDKVYTKSSHLKAHKRTHTGEKPYVCTWEGCIWRFARSDELTRHYRKHTGVKPFRC 342
                |:.|.|.|.|||.|||.:|:|.||||:||.|.||.|.|.|.|||||.||.|.||..:|::|
Human   281 RPYCCNYENCGKAYTKRSHLVSHQRKHTGERPYSCNWESCSWSFFRSDELRRHMRVHTRYRPYKC 345

  Fly   343 QLCTRSFSRSDHLSLHMRRH 362
            ..|:|.|.|||||..|.:.|
Human   346 DQCSREFMRSDHLKQHQKTH 365

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42741NP_611747.2 COG5048 <273..>352 CDD:227381 41/92 (45%)
zf-C2H2 280..304 CDD:278523 12/37 (32%)
C2H2 Zn finger 282..304 CDD:275368 12/21 (57%)
zf-H2C2_2 296..>313 CDD:290200 10/16 (63%)
C2H2 Zn finger 312..334 CDD:275368 14/21 (67%)
zf-H2C2_2 326..351 CDD:290200 12/24 (50%)
C2H2 Zn finger 342..362 CDD:275368 10/19 (53%)
KLF17NP_775755.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..48 9/20 (45%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 239..279 5/40 (13%)
COG5048 282..>350 CDD:227381 37/67 (55%)
zf-C2H2 283..307 CDD:278523 12/23 (52%)
C2H2 Zn finger 285..307 CDD:275368 12/21 (57%)
zf-C2H2 313..337 CDD:278523 15/23 (65%)
C2H2 Zn finger 315..337 CDD:275368 14/21 (67%)
zf-H2C2_2 329..352 CDD:290200 11/22 (50%)
zf-C2H2 343..365 CDD:278523 10/21 (48%)
C2H2 Zn finger 345..365 CDD:275368 10/19 (53%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 356..389 5/10 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165151406
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR23235
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.940

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