Protein Alignment SLC27A1 and CG11453

DIOPT Version :9

• Sequence 1: XP_011526302.1
• Gene: SLC27A1 / 376497
• HGNCID: 10995
• Length: 658
• Species: Homo sapiens
• Sequence 2: NP_650832.1
• Gene: CG11453 / 42355
• FlyBaseID: FBgn0038734
• Length: 539
• Species: Drosophila melanogaster
• Alignment Length: 579
• Identity: 143/579 - (24%)
• Similarity: 223/579 - (38%)
• Gaps: 113/579 - (19%)

Human    77 TIPRIFQAVVQRQPERLALVDAGTGECWTFAQLDAYSNAVANLFRQLGFAPGDVVAI-------- 133
            :|.:|..|.::..|..:..:....|...|..:...::..:|...:.:|....|||.|
  Fly    29 SIGKILFAFMRNHPNSICQISDTEGTALTNGEAITFAIRIAQQLKAMGLKQDDVVGIVGTNTTYL 93

Human   134 -------FLEGRP-EFVGLWLGLAKAGMEAALLNV-NLRREPLAFCLGTSGAKALIFGGEMVAAV 189
                   .|.|.| ..|..|..      |..:.:: ::.|..|.||.|....:..|....:.:.|
  Fly    94 MPVVLGCLLNGTPFHAVSPWQD------EDTIKHLFSITRPKLIFCDGKCFQRLSIIARILKSHV 152

Human   190 AEVSGH-LGKSLIKFCSGDLGPEGILPDTHLLDPLLKEASTAPLAQIPSK---GMDDRLFYIYTS 250
            ..:..| ||...::               .||:|     :||.|..:|..   |.|..:..:.||
  Fly   153 YTLKDHRLGMPRVE---------------DLLEP-----TTAELYYVPETLLLGGDHTVAILCTS 197

Human   251 GTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYHSAGNIIGVGQCLIYGLTVVLRK 315
            ||||||||..:.:|..  :..||.    :...|||.....:..|||....:..| .:|.|.::..
  Fly   198 GTTGLPKAVCISNSAC--LFDFGF----VTGQDVLLSFSTIDWSAGMFNMLFSC-CHGSTRIITD 255

Human   316 KFSASRFWDDCI-KYNCTINGVRHCRLLCLVVQYIGEICRYLLKQPVREAERRHRVR-LAVGNG- 377
            :.....:....: ||..|        ||.:|.|.:..    |||.|....:|...:| ::||.|
  Fly   256 RPYTPEYMIQLVEKYKVT--------LLTVVPQQVAS----LLKTPTLNKQRLASIRFVSVGGGS 308

Human   378 LRPAIWEEFTERFGVRQIGEFYGATECNCSIANMD-GKVGSCGFNSRILPHVYPIRLVKVNEDTM 441
            ...|...:..|.....||...|..|||....|||. .|..|.|   ||:|.|    .||:.::..
  Fly   309 CYVANLLKLQEFLITGQISYGYALTECGGVAANMGVAKPSSVG---RIVPGV----RVKILDEAG 366

Human   442 ELLRDAQGLCIPCQAGEPG-LLV--GQINQQDPLRRFDGYVSESATSKKIA--HSVFSKGDSAYL 501
            ..|..          ||.| :||  |::        ::||.:....||::.  ...|..||..|
  Fly   367 RSLGH----------GETGEILVHNGKV--------WNGYYANPNESKRMQDYQGWFHTGDMGY- 412

Human   502 SGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLGQTDVAVYGVAVPGVEGKAGMA 566
                  .|...|::..:|..|..|:.|...|..|:|.|::.|....:..|:|: ...|:|....|
  Fly   413 ------FDNENYLHIVERKEDLLRFHGAQYSPQEIEQVIAELPDVIEACVFGL-WNEVDGDPAAA 470

Human   567 AVAD-PHSLLDPNAIYQELQKVLAPYARPIF--LRLLPQVDTTGTFKI--QKTRLQREG 620
            ||.. |.|.|....|.:.:.|.|....:.:.  :..||::..||:.|:  |:.|.|..|
  Fly   471 AVVKIPGSRLTEMDIVEYVAKRLVVDHKQLHCGVFFLPELPKTGSGKVLRQQARDQALG 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC27A1	XP_011526302.1	PRK08279	42..656	CDD:236217	143/579 (25%)
		metallo-hydrolase-like_MBL-fold	64..>135	CDD:304873	12/72 (17%)
		AFD_class_I	101..623	CDD:302604	139/555 (25%)
CG11453	NP_650832.1	CaiC	18..530	CDD:223395	143/579 (25%)
		Firefly_Luc_like	46..519	CDD:213279	135/550 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149018
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840