Protein Alignment SLC27A1 and CG11391

DIOPT Version :9

• Sequence 1: XP_011526302.1
• Gene: SLC27A1 / 376497
• HGNCID: 10995
• Length: 658
• Species: Homo sapiens
• Sequence 2: NP_650830.1
• Gene: CG11391 / 42353
• FlyBaseID: FBgn0038732
• Length: 542
• Species: Drosophila melanogaster
• Alignment Length: 563
• Identity: 129/563 - (22%)
• Similarity: 223/563 - (39%)
• Gaps: 93/563 - (16%)

Human    77 TIPRIFQAVVQRQPERLALVDAGTGECWTFAQLDAYSNAVANLFRQLGF-APGDVVAIFLEGRPE 140
            |:.:|....:||||:|:..:........|..|:...:..:....|..|| ...|:|.:.......
  Fly    33 TVGQIIFRQLQRQPQRIFQISHTDNTRLTRFQMLQNAAKIGCYLRDQGFKKETDLVGLMARNSTH 97

Human   141 FVGLWLGLAKAGMEAALLNVNLRR----------EPLAFCLGTSG-AKALIFGGEMVAAVAEVSG 194
            ...|..|....|.....:|.||..          .|...|..|:. .|....|..:.|.:..|:|
  Fly    98 VGALAYGCLFNGTPFHAVNPNLEHNTISSLYKITRPRILCCDTADYEKIKDIGASLGALIITVNG 162

Human   195 HLGKSLIKFCSGDLGPEGILPDTHLL-DPLLKEASTAPLAQIPSKGMDDRLFYIYTSGTTGLPKA 258
            .|              .|::....:| :||..:...|..    .:|:|..:..:.:|||||.|||
  Fly   163 KL--------------PGVISVADILQNPLPDDYEPAQF----QRGVDRTMAILCSSGTTGTPKA 209

Human   259 AIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYHSAGNIIGVGQCLIYGLTVVLRKKFSASRFW 323
            ..:.:||    ..|..|:| :.:.||.|....|....|.|..|...:...:.::..:.||.:.|.
  Fly   210 VTLSNSR----KLFEMHSY-LGSDDVQYAPSTLDWLTGLITLVTAAVFGTVRLISSEMFSTAHFL 269

Human   324 DDCIKY--NCTINGVRHCRLLCLVVQYIGEICRYLLKQPVREAERRHRVRLAVGNGLRPAI--WE 384
            |.|.::  :.||....|..:|.        .|.....|.:|..:   .:..|.|:.|...:  .:
  Fly   270 DICEQHEVSWTIMANSHVAMLA--------NCPKTSAQKLRSLK---HLLFAGGHCLVATLKKMQ 323

Human   385 EFTERFGVRQIGEFYGATECNCSIA-NMD--GKVGSCGFNSRILPHVYPIRLVKVNEDTMELLRD 446
            .|....|:  :...||.||....:: |.|  .|..|.|   |::.:: .:::|    |:...|:.
  Fly   324 SFLHGSGI--LRNAYGLTEVGTLVSYNYDTQSKPTSVG---RLMANI-RVKIV----DSSGQLQG 378

Human   447 AQGLC-IPCQAGEPGLLVGQINQQDPLRRFDGYVSESATSKKIAHSVFSKGDSA--YLSGDVLVM 508
            .:||. |.|..|:|               :.|||.....:.::.       |||  |.:|||...
  Fly   379 PKGLGEILCHNGQP---------------WSGYVGNPLATAEMR-------DSAGWYHTGDVGYF 421

Human   509 DELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLGQTDVAVYGVAVPGVEGKAGMAAVA-DPH 572
            ||..|::..:|..|..::.|......|||.|::::....:|.|:|: ....||.|..|:|. ...
  Fly   422 DEDHYLHIVERKKDMLKYLGMMYYPHEVEEVIAQMPDVAEVCVFGI-FRETEGDAAAASVVLRSG 485

Human   573 SLLDPNAIYQELQKVLAPYARPIF--LRLLPQVDTTGTFKIQK 613
            |.|||..:.|.::|.::...:.:.  ::.:||:..:...|:.:
  Fly   486 SKLDPKHVEQYVRKNVSVQFKHLHGGVQFVPQLAKSANGKVNR 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC27A1	XP_011526302.1	PRK08279	42..656	CDD:236217	129/563 (23%)
		metallo-hydrolase-like_MBL-fold	64..>135	CDD:304873	14/58 (24%)
		AFD_class_I	101..623	CDD:302604	122/539 (23%)
CG11391	NP_650830.1	CaiC	24..541	CDD:223395	129/563 (23%)
		AFD_class_I	51..527	CDD:302604	122/542 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149015
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840