Protein Alignment SLC27A1 and CG18586

DIOPT Version :9

• Sequence 1: XP_011526302.1
• Gene: SLC27A1 / 376497
• HGNCID: 10995
• Length: 658
• Species: Homo sapiens
• Sequence 2: NP_647993.2
• Gene: CG18586 / 38659
• FlyBaseID: FBgn0035642
• Length: 545
• Species: Drosophila melanogaster
• Alignment Length: 537
• Identity: 110/537 - (20%)
• Similarity: 192/537 - (35%)
• Gaps: 163/537 - (30%)

Human   110 DAYSNA--VANLFRQLGFAPGDVV---------------AIFLEGRPEFVGLWLGLAKAGMEAAL 157
            |.:.||  ||:..|.:|....|:|               |.|..|.|..     .|..|..||.:
  Fly    69 DLHMNAMRVASYMRNMGLGQTDIVGVMGRHTTHQSAVAYACFFNGTPLH-----ALHNAYEEACI 128

Human   158 LNV-NLRREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLD 221
            ..: .:.:..|.||.|....|......::...:..:..|              |.|.:
  Fly   129 AKLFGITKPRLIFCDGDEYEKVKSATKDLQVTIVTMRNH--------------PRGSV------- 172

Human   222 PLLKEASTAPLAQ--IPSK---GMDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQA 281
             .:::..|.|:.|  .|.:   |:|..|..:.:|||:|.|||..:.:|.
  Fly   173 -RIQDVLTTPVMQNFQPLRLKDGIDHTLAILSSSGTSGFPKAVTISNSH---------------- 220

Human   282 ADVLYDCLPLYHSAGNIIGVGQCLIY--GLTVVLRK-KFSASRFWDDCIKYN----CTINGVRHC 339
             .::.|.:.:.:|  ||......|.:  ||::.:.. .||.:....|| .::    |...|....
  Fly   221 -KIIVDYMAINNS--NIQYTSSTLDWCSGLSMAITSGVFSTTSIIADC-DFDPGLFCRAIGKYRI 281

Human   340 RLLCLVVQYI-----------------------GEICRYLLKQPVREAERRHRVRLAVGNGLRPA 381
            .::.|...|:                       |..|..       |.:|:.|.||:
  Fly   282 SMVLLSSSYLAIFANCPEFESADLSSLNYVIFGGSSCSL-------EVQRKVRSRLS-------- 331

Human   382 IWEEFTERFGVRQIGEF-YGATECNCSIA---NMDGKVGSCGFNSRILPHVYPIRLVKVNEDTME 442
                       .....| ||.||.|.:.:   |.|.|..|.|         ..||.:|:.
  Fly   332 -----------HDCLNFCYGLTELNSAGSVNLNFDEKPNSVG---------RAIRGIKIK----- 371

Human   443 LLRDAQGLCIPCQAGEPGLLVGQI---NQQDPLRRFDGYVSESATSKKIAHSVFSKGDSAYLSGD 504
             :.|.||     :|.||. :||:|   |.|    ::.||......:::|..|     ::...:||
  Fly   372 -VIDEQG-----EAQEPN-VVGEICFHNSQ----KWAGYYKNPDETRQIQDS-----ENWIHTGD 420

Human   505 VLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLGQTDVAVYGVAVPGVEGKAGMAAVA 569
            :..:|:.||::..||..|..:::......:|:|.|::.:....:..|:|:..|....:|..:.|.
  Fly   421 LGYVDKDGYLFVIDRLKDMLKYQNIMYYPSEIENVIAEMPNVLEACVFGIWDPVNGDEAAASLVK 485

Human   570 DPHSLLDPNAIYQELQK 586
            .|.:.|:...:.:.::|
  Fly   486 KPGTQLEAQDVVEYVRK 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC27A1	XP_011526302.1	PRK08279	42..656	CDD:236217	110/537 (20%)
		metallo-hydrolase-like_MBL-fold	64..>135	CDD:304873	10/41 (24%)
		AFD_class_I	101..623	CDD:302604	110/537 (20%)
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	110/537 (20%)
		AFD_class_I	55..530	CDD:302604	110/537 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149012
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930