Protein Alignment SLC27A1 and CG9993

DIOPT Version :9

• Sequence 1: XP_011526302.1
• Gene: SLC27A1 / 376497
• HGNCID: 10995
• Length: 658
• Species: Homo sapiens
• Sequence 2: NP_611518.1
• Gene: CG9993 / 37358
• FlyBaseID: FBgn0034553
• Length: 543
• Species: Drosophila melanogaster
• Alignment Length: 561
• Identity: 133/561 - (23%)
• Similarity: 226/561 - (40%)
• Gaps: 77/561 - (13%)

Human    77 TIPRIFQAVVQRQPERLALVDAGTGECWTFAQLDAYSNAVANLFRQLGFAPGDVVAIFLEGRPEF 141
            |:..:...:::...:::..|...|||..|.:||...|..:|:.|::|....||||.|..:.....
  Fly    27 TLGEVALIILRLYSDKVMQVYDPTGEELTGSQLLEQSRRLAHAFQRLKLQRGDVVGISAKNTTYL 91

Human   142 VGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSG 206
            ..:.:.....|.....|:.:...|..|:....:..|.:....:....::.|     ||.:||.:.
  Fly    92 TEVVIAALLNGTPINPLHPDFDAETTAYMFEITKPKVIFCDLDNYQTLSAV-----KSSLKFKTE 151

Human   207 DLGPEGILPDTHLLDPLLKEASTA----PLAQIPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRYY 267
            .:...|.||....:..||.:..|.    .|...|....||..|.|.:||.|||||..    :|.:
  Fly   152 IILLTGTLPGVRNIQDLLADGCTGYDEKTLFACPHLCGDDTAFIITSSGVTGLPKGV----TRSH 212

Human   268 RMAAFGHHAYRMQAADVLYDCL-PLYHSAGNIIGVGQCLIYGL-TVVLRKKFSASRFWDDCIKYN 330
            |.........::..:|.:..|. |||. ...|..:...|:.|. .::..:.||.: ::.|.::
  Fly   213 RSLLNSAKIPQLFTSDTVLFCFSPLYW-ISCIFTLLASLVNGCRRIITNRPFSVA-YFADLVE-- 273

Human   331 CTINGVRHCRLLCLVVQYIGEICRYLLKQPVRE--AERRHRVRLAV--GNGLRPAIWEEFTERFG 391
                  ||.....|.|.:...:   |.|.|.|:  |.:...|:..|  |:.:...||.:..|..|
  Fly   274 ------RHQVSFVLTVPHHMAL---LAKSPERQELAAKMQCVQSFVCSGSKVPMGIWRQLYELLG 329

Human   392 VRQIGEFYGATECNCSIANMDGKVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCI-PCQ 455
            ..:....||.||......|:.|.:||.|   |:|.:| .:|:|           |..|..: |.|
  Fly   330 ANRFAVLYGLTETGGISKNVGGPLGSEG---RLLRNV-QVRVV-----------DPHGQSLGPNQ 379

Human   456 AGEPGLLVGQINQQDPLRRFDGYVSESATSKKIAHSVFSKGDSAY-LSGDVLVMDELGYMYFRDR 519
            .|:  :|| ::|     .|:.||......::     |....|..: |:||....|:.|.::|:.|
  Fly   380 TGQ--ILV-RLN-----LRWGGYYHNPQETQ-----VTVTPDGKWLLTGDHGYFDDEGCLHFQSR 431

Human   520 SGDTFRWRGENVSTTEVEGVLSRLLGQTDVAVYGVAVPGVEGKAGMAAVADPHSLLDPNAIYQEL 584
            ..|.|::....:...::|.|:..|.|..:|||:|:. ..|.......||......|.......::
  Fly   432 DTDVFKYNHFPIYPKQIEDVILHLPGVHEVAVFGIP-DEVSTNLTACAVVRNEDELGAQLTEADV 495

Human   585 QKVLAPYARPIF-LRLLPQVDTTGTF------KIQKTRLQR 618
            :.|:|.:....| :|       .|.|      |.|.:::||
  Fly   496 KGVVAQHLSDAFHIR-------GGVFFVDNLPKTQNSKVQR 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC27A1	XP_011526302.1	PRK08279	42..656	CDD:236217	133/561 (24%)
		metallo-hydrolase-like_MBL-fold	64..>135	CDD:304873	17/57 (30%)
		AFD_class_I	101..623	CDD:302604	130/537 (24%)
CG9993	NP_611518.1	CaiC	21..532	CDD:223395	133/561 (24%)
		AFD_class_I	45..528	CDD:302604	130/540 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149013
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840