DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CNBP and ZCCHC3

DIOPT Version :9

Sequence 1:	NP_001188992.1	Gene:	CNBP / 37646	FlyBaseID:	FBgn0034802	Length:	165	Species:	Drosophila melanogaster
Sequence 2:	NP_149080.2	Gene:	ZCCHC3 / 85364	HGNCID:	16230	Length:	403	Species:	Homo sapiens

Alignment Length:	131	Identity:	36/131 - (27%)
Similarity:	51/131 - (38%)	Gaps:	29/131 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 YKCNRPGHFARDCSLGGGGG-----PGGVGGGGGGGGGGMRGNDGGGMRRNREKCYKCNQFGHFA 67
            |||        :..|..|.|     ||....|...|....:|..        :.|:||....|.:
Human   297 YKC--------EIELRQGEGGVRHLPGAFFLGAERGYSWYKGQP--------KTCFKCGSRTHMS 345

  Fly    68 RACPEEAERCYRCNGIGHISKDCTQADNPTCYRCNKTGHWVRNCPEAVNERGPTNVSCYKCNRTG 132
            .:|.:  :||:||...||:|..|.:  ...|..|.|.||....||:||:    .:|:.......|
Human   346 GSCTQ--DRCFRCGEEGHLSPYCRK--GIVCNLCGKRGHAFAQCPKAVH----NSVAAQLTGVAG 402

  Fly   133 H 133
            |
Human   403 H 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CNBP	NP_001188992.1	PTZ00368	6..161	CDD:173561	36/131 (27%)
ZCCHC3	NP_149080.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..158
ZCCHC3	NP_149080.2	AIR1	<333..>386	CDD:331526	18/56 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1535084at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820