DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CNBP and glh-1

DIOPT Version :9

Sequence 1:	NP_001188992.1	Gene:	CNBP / 37646	FlyBaseID:	FBgn0034802	Length:	165	Species:	Drosophila melanogaster
Sequence 2:	NP_491963.1	Gene:	glh-1 / 172414	WormBaseID:	WBGene00001598	Length:	763	Species:	Caenorhabditis elegans

Alignment Length:	174	Identity:	61/174 - (35%)
Similarity:	75/174 - (43%)	Gaps:	36/174 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 GHFARDCSLGGGGGPG----GVGGGGGGGGGGM----RGNDGGGMRRNREKCYKCNQFGHFARAC 70
            |...:..:.||.||.|    |.|.|||..|||.    .|..|||.|.|  .|:.|.|.||.:..|
Worm   111 GSGEKSSAFGGSGGFGGSATGFGSGGGSFGGGNSGFGEGGHGGGERNN--NCFNCQQPGHRSSDC 173

  Fly    71 PE-----EAERCYRCNGIGHISKDCTQADNPTCYRCNKTGHWVRNCPEAVN-------------- 116
            ||     |...||.|...||.|::||:...|   |..:||.:........|
Worm   174 PEPRKEREPRVCYNCQQPGHTSRECTEERKP---REGRTGGFGGGAGFGNNGGNDGFGGDGGFGG 235

  Fly   117 --ERGPTNVSCYKCNRTGHISKNCPETSKTCYGCGKSGHLRREC 158
              ||||  :.|:.|...||.|..|||..:.|:.||:.||...||
Worm   236 GEERGP--MKCFNCKGEGHRSAECPEPPRGCFNCGEQGHRSNEC 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CNBP	NP_001188992.1	PTZ00368	6..161	CDD:173561	61/174 (35%)
glh-1	NP_491963.1	zf-CCHC	158..175	CDD:278525	7/18 (39%)
		zf-CCHC	183..200	CDD:278525	7/16 (44%)
		ZnF_C2HC	243..259	CDD:197667	6/15 (40%)
		zf-CCHC	262..279	CDD:278525	7/16 (44%)
		DEADc	343..558	CDD:238167
		DEXDc	359..561	CDD:214692
		Helicase_C	579..701	CDD:278689
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1052
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D623350at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.870