Protein Alignment CG3788 and UPP1

DIOPT Version :10

• Sequence 1: NP_611738.1
• Gene: CG3788 / 37644
• FlyBaseID: FBgn0034800
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_003355.1
• Gene: UPP1 / 7378
• HGNCID: 12576
• Length: 310
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 144/301 - (47%)
• Similarity: 199/301 - (66%)
• Gaps: 5/301 - (1%)

  Fly    46 EEAKESTLCG---LNPCLKCLQPDILYHLGLNTETTDFPKVFGDVRFVCMGGTPGRMENFAYYVM 107
            |:|:....|.   |||.:..::.|||||..|.|...:||.:||||:|||:||:|.||:.|...|.
Human     9 EKAESHNDCPVRLLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVG 73

  Fly   108 QEIGLKINAATKLRNISEAGQRFSLFKVGPVLCASHGMGCPSISILLHELIKMMYHAKCKDPVFI 172
            .|:||.. ......||.....|::::||||||..|||||.|||||:||||||::|:|:|.:...|
Human    74 AELGLDC-PGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTII 137

  Fly   173 RIGTSGGIGVEPGTVIISSEAIDGRLNPVHEILVHGVSVQHASQLDESLADEIKMCHDPCKDKYE 237
            |||||||||:|||||:|:.:|:|.......|.:|.|..|...:.|::.|..|:.:|.....: :.
Human   138 RIGTSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSE-FT 201

  Fly   238 AVIGRTLCAHDFYEGQSRLDGAFCEYTPEMKKSYLETLQSQQVKNIEMESLAFAALTSRANIRGA 302
            .|:|.|:|..||||||.|||||.|.||.:.|::|||...:..|:||||||..|||:.|...::.|
Human   202 TVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAA 266

  Fly   303 VVCVAILNRLNGDQIKTPHDVLSKWEKRPQELVARYIRKVL 343
            ||||.:||||.||||.:|.:|||::::|||.||:.:|:|.|
Human   267 VVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIKKKL 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3788	NP_611738.1	euk_UDPppase	57..345	CDD:130780	140/287 (49%)
UPP1	NP_003355.1	UP_hUPP-like	31..305	CDD:350163	136/275 (49%)