Protein Alignment ReepA and REEP6

DIOPT Version :9

• Sequence 1: NP_001188988.1
• Gene: ReepA / 37643
• FlyBaseID: FBgn0261564
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_001316485.1
• Gene: REEP6 / 92840
• HGNCID: 30078
• Length: 211
• Species: Homo sapiens
• Alignment Length: 220
• Identity: 57/220 - (25%)
• Similarity: 90/220 - (40%)
• Gaps: 66/220 - (30%)

  Fly   130 FNTACICSLIVIFLAPRTCAQSLLFPAFRLFCGTLYPAYASYKAVRTKDVKEYVKWMMYWIVFAF 194
            :..:.:|:||                      |.:||||||.||:.:....:...|:.||:|:|.
Human    52 YGASLLCNLI----------------------GFVYPAYASIKAIESPSKDDDTVWLTYWVVYAL 94

  Fly   195 FTCIETFTDIFISWLPFYYEVKVALVFWLLSPAT-KGSSTLYRKFVHPMLTRHEQEIDEYVNQAK 258
            |...|.|:|:.:||.||||..|.|.:.:.::|.. .|:..||::.|.|:..||...:|..:|...
Human    95 FGLAEFFSDLLLSWFPFYYVGKCAFLLFCMAPRPWNGALMLYQRVVRPLFLRHHGAVDRIMNDLS 159

  Fly   259 ERGYSAVLQLGSKGVNYATNVLMQTAIKGGGNLVQTIKRSYSLSDLSEPDMHRTQDELDDVMMSS 323
            .|...|     :.|:.              .|::|.:.||                      .:.
Human   160 GRALDA-----AAGIT--------------RNVLQVLARS----------------------RAG 183

  Fly   324 MTSSAVVMRSTATGARLLRPRNQTP 348
            :|..||...||...|. |:| :|||
Human   184 ITPVAVAGPSTPLEAD-LKP-SQTP 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ReepA	NP_001188988.1	TB2_DP1_HVA22	158..241	CDD:281172	31/83 (37%)
REEP6	NP_001316485.1	TB2_DP1_HVA22	66..143	CDD:308643	29/76 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	190..211		8/19 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1473891at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820