Protein Alignment ReepA and REEP2

DIOPT Version :10

• Sequence 1: NP_001188988.1
• Gene: ReepA / 37643
• FlyBaseID: FBgn0261564
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_001258732.1
• Gene: REEP2 / 51308
• HGNCID: 17975
• Length: 254
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 109/259 - (42%)
• Similarity: 142/259 - (54%)
• Gaps: 47/259 - (18%)

  Fly   159 LFCGTLYPAYASYKAVRTKDVKEYVKWMMYWIVFAFFTCIETFTDIFISWLPFYYEVKVALVFWL 223
            |..|||||||:|||||:||:||||||||||||||||||..||.|||.:||.|||:|:|:|.|.||
Human    12 LIFGTLYPAYSSYKAVKTKNVKEYVKWMMYWIVFAFFTTAETLTDIVLSWFPFYFELKIAFVIWL 76

  Fly   224 LSPATKGSSTLYRKFVHPMLTRHEQEIDEYVNQAKERGYSAVLQLGSKGVNYATNVLMQTAIKGG 288
            |||.|||||.||||||||.|:..|:|||||:.||:::.|..::::|.:|:|.|.|..:..|.||.
Human    77 LSPYTKGSSVLYRKFVHPTLSNKEKEIDEYITQARDKSYETMMRVGKRGLNLAANAAVTAAAKGQ 141

  Fly   289 GNLVQTIKRSYSLSDLSEPDMHRTQDELDDVMMSSMTSSAVVMRSTATGARLLRPRNQTPVGRSG 353
            |.|.:.: ||:|:.||:                                  |:|..:..|:.|..
Human   142 GVLSEKL-RSFSMQDLT----------------------------------LIRDEDALPLQRPD 171

  Fly   354 SGTRHSTGMYFTEVDVTAKNAGDFNYNIRSQDDISSGYSSAEPVSGLSRTSSMTNASKARAKSK 417
            ...|.|.|....    |.::.||        |...|..||..|....:..|......||..::|
Human   172 GRLRPSPGSLLD----TIEDLGD--------DPALSLRSSTNPADSRTEASEDDMGDKAPKRAK 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ReepA	NP_001188988.1	TB2_DP1_HVA22	166..242	CDD:460820	59/75 (79%)
REEP2	NP_001258732.1	TB2_DP1_HVA22	19..94	CDD:460820	58/74 (78%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	167..254		16/69 (23%)