DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and Cfi

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_077071.1	Gene:	Cfi / 79126	RGDID:	620429	Length:	604	Species:	Rattus norvegicus

Alignment Length:	273	Identity:	81/273 - (29%)
Similarity:	110/273 - (40%)	Gaps:	57/273 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 IVGGTKASGKEFPFMALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNF 166
            :|||..|...::|:...|        |......|||..:...::||||||:.....:
  Rat   362 VVGGKPAEMGDYPWQVAI--------KDGDRITCGGIYIGGCWILTAAHCVRPSRYR-------- 410

  Fly   167 DSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVEL-----DRKAE 226
               .:.|....||:........||.  |...|||..|:...    ::|||||||:     .::.|
  Rat   411 ---NYQVWTSLLDWLKPNSQLAVQG--VSRVVVHEKYNGAT----YQNDIALVEMKKHPGKKECE 466

  Fly   227 FNDHVAAVCLP--PDSGNDVQQVTAAGWGFTADGVKSSHL------LKVNLQRF-SDEVCQKRLR 282
            ..:.|.| |:|  |.......:...:|||...|..|...|      |..|..|| .....:|.::
  Rat   467 LINSVPA-CVPWSPYLFQPNDRCIISGWGREKDNQKVYSLRWGEVDLIGNCSRFYPGRYYEKEMQ 530

  Fly   283 FSIDTRTQFCAGSMSSQADTCNGDSGGPIF---VQHPLYPCLKQVIGIVSYGLVCGSQGLPSVYT 344
                     |||:.....|.|.||||||:.   |.:..|     |.||||:|..||....|.|||
  Rat   531 ---------CAGTSDGSIDACKGDSGGPLVCKDVNNVTY-----VWGIVSWGENCGKPEFPGVYT 581

  Fly   345 KVHLYTDWIESIV 357
            :|..|.|||...|
  Rat   582 RVASYFDWISYYV 594

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	80/270 (30%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	78/267 (29%)
Cfi	NP_077071.1	FIMAC	46..111	CDD:214493
		SR	117..220	CDD:214555
		SRCR	122..219	CDD:278931
		LDLa	228..258	CDD:197566
		LDLa	264..298	CDD:294076
		Tryp_SPc	361..590	CDD:214473	78/267 (29%)
		Tryp_SPc	362..591	CDD:238113	79/268 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910