DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and f7

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001072819.1	Gene:	f7 / 780280	XenbaseID:	XB-GENE-5787186	Length:	452	Species:	Xenopus tropicalis

Alignment Length:	369	Identity:	107/369 - (28%)
Similarity:	159/369 - (43%)	Gaps:	79/369 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 CDNGTGECKELTPS---DCPVIFYNQHLIGAEVKYCD-EFNDIVCCPIP------LDHQNLKPAE 77
            |.|| |.|.:...|   .||        :|.|.::|: ...|::.|...      ..|.|...:.
Frog   117 CMNG-GTCFDQHQSYICTCP--------MGYEGRHCETNLRDMLKCIYDNGQCEHFCHDNSSTSR 172

  Fly    78 QTRPFE--------KQCKQYNEVRSACQSTPF---------IVGGTKASGKEFPFMALIGTHRPN 125
            |....|        ..|:.  .|...|...|.         ||||......|.|:.||:
Frog   173 QCSCAEGYKLGADGLSCEP--TVNYPCGKIPVLKNVNKRARIVGGDMCPKGECPWQALL------ 229

  Fly   126 KSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKFVVRLGELDYNSTTDDALVQ 190
             ..::| :.|||:::.|.:|:||||||:.       |..|    |..|.|||  :...|.:...|
Frog   230 -MYNEI-FICGGTLIAPNWVITAAHCLKP-------LPEN----KLTVVLGE--HRIGTPEGTEQ 279

  Fly   191 DFRVVNYVVHPGY---DTEDEEQGFKNDIALVELDRKAEFNDHVAAVCLPPDSGNDVQQV----- 247
            :.:|...::|..|   .|.::     |||||::|.....:.|:|..:|| |:....||::
Frog   280 ESKVSKIIMHEHYYGSKTNND-----NDIALLKLTTPVNYTDYVVPLCL-PEKQFAVQELLSIRY 338

  Fly   248 -TAAGWG-FTADGVKSSHLLKVNLQRFSDEVCQKRLRFSIDTRTQFCAGSMSSQADTCNGDSGGP 310
             |.:||| ....|.....|.:|.|.|...:.|.::.:.:| ::..||||......|:|.||||||
Frog   339 STVSGWGRLLESGATPELLQRVQLPRVKTQDCIRQTQMNI-SQNMFCAGYTDGSKDSCKGDSGGP 402

  Fly   311 IFVQHPLYPCLKQVIGIVSYGLVCGSQGLPSVYTKVHLYTDWIE 354
            ...|   |.....:.||||:||.|..:....|||:|..||:||:
Frog   403 HATQ---YKNTHFLTGIVSWGLGCAKKEKYGVYTRVSRYTEWIK 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	86/263 (33%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	84/260 (32%)
f7	NP_001072819.1	Gla	67..107	CDD:366184
		EGF_CA	108..144	CDD:238011	10/35 (29%)
		FXa_inhibition	153..189	CDD:373209	5/35 (14%)
		Tryp_SPc	212..445	CDD:238113	86/263 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910