DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and f9b

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001035400.1	Gene:	f9b / 678552	ZFINID:	ZDB-GENE-060421-7346	Length:	507	Species:	Danio rerio

Alignment Length:	421	Identity:	102/421 - (24%)
Similarity:	162/421 - (38%)	Gaps:	114/421 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 CDNGTGECKE---LTPSDCPVIFYNQHLIGAEVKYC-------------DEFNDIVC-CP----I 66
            |.|| |:|::   .....||..|..::......|.|             |:....|| |.    :
Zfish    97 CQNG-GKCEDGMNTYTCWCPARFSGKNCELEMAKQCHVNNGGCMHFCIVDKIYGAVCDCAEGYRL 160

  Fly    67 PLDHQNLKPAEQ---------------TRPFEK-------------QCKQYNEVRSA-------- 95
            .:|.::.:|..|               :|..|.             ...:||...|:
Zfish   161 AVDGRSCEPRGQYPCGRLGKIIAQTLNSRALESTETVNQNQTISHINGTEYNTTESSPTDLSEMN 225

  Fly    96 CQSTP------------------------FIVGGTKASGKEFPFMALIGTHRPNKSKSDINWDCG 136
            ..|||                        .||||.:|...|.|:. ::...:.||...     ||
Zfish   226 STSTPRNSLQNVSSSPILTNINNTTNNKYRIVGGDEAIPGEIPWQ-VVFLEKVNKIVF-----CG 284

  Fly   137 GSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHP 201
            ||::..::|:|||||:|..:.            .|.:|:||.|.:..  :....|..:..|.:||
Zfish   285 GSLLSEEWVITAAHCVEGKQG------------SFFIRVGEHDVSKM--EGTESDHGIEEYHIHP 335

  Fly   202 GYDTEDEEQGFKNDIALVELDRKAEFNDHVAAVCLPPDSGND-----VQQVTAAGWG-FTADGVK 260
            .|::  :...:.:||||::|.:.....|:...:||......:     .:....:||| ....|::
Zfish   336 RYNS--QRSLYNHDIALLKLKKPVILFDYAVPICLGSKDFTENLLQSAENSLVSGWGRLRYGGIE 398

  Fly   261 SSHLLKVNLQRFSDEVCQKRLRFSIDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQVI 325
            |:.|.||.|.......|:.....|| :|..||||..:.:.|.|.||||||...:   |.....:.
Zfish   399 SNVLQKVELPYVDRIKCKGSSTDSI-SRFMFCAGYSTVRKDACQGDSGGPHATR---YKDTWFLT 459

  Fly   326 GIVSYGLVCGSQGLPSVYTKVHLYTDWIESI 356
            ||||:|..|..:|...:||::..|..||.:|
Zfish   460 GIVSWGEECAKEGKYGIYTRISKYMAWITNI 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	76/259 (29%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	74/256 (29%)
f9b	NP_001035400.1	GLA	23..86	CDD:214503
		EGF_CA	88..124	CDD:238011	8/27 (30%)
		FXa_inhibition	131..167	CDD:291342	6/35 (17%)
		Tryp_SPc	255..487	CDD:214473	74/257 (29%)
		Tryp_SPc	256..490	CDD:238113	76/259 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910