DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and Tmprss11d

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001028824.2	Gene:	Tmprss11d / 64565	RGDID:	620654	Length:	417	Species:	Rattus norvegicus

Alignment Length:	292	Identity:	93/292 - (31%)
Similarity:	126/292 - (43%)	Gaps:	74/292 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 NEVRSACQSTP--------FIVGGTKASGKEFPF---MALIGTHRPNKSKSDINWDCGGSVVHPK 143
            |.:...|.:.|        .|:|||:|...::|:   :.|...|.           |||:::...
  Rat   166 NVLTQECGARPDLITLSEERIIGGTQAETGDWPWQVSLQLNNVHH-----------CGGTLISNL 219

  Fly   144 FVLTAAHCLETDESKAERLDPNFD----SPKFVVR----LGELDYNSTTDDALVQDFRVVNYVVH 200
            :|||||||..: .|..::....|.    ||:..||    |...:|||.|.|
  Rat   220 WVLTAAHCFRS-YSNPQQWTATFGVSTISPRLRVRVRAILAHAEYNSITRD-------------- 269

  Fly   201 PGYDTEDEEQGFKNDIALVELDRKAEFNDHVAAVCLP-------PDSGNDVQQVTAAGWG-FTAD 257
                         ||||:|:|||...|..::..||||       |||   |..||  ||| .|..
  Rat   270 -------------NDIAVVQLDRPVTFTRNIHRVCLPAATQNIIPDS---VAYVT--GWGSLTYG 316

  Fly   258 GVKSSHLLKVNLQRFSDEVCQKRLRFSIDTRT-QFCAGSMSSQADTCNGDSGGPIFVQHPLYPCL 321
            |...::|.:..::..|.|||.:...:...... ..|||..|...|.|.||||||: ||..... |
  Rat   317 GNTVTNLQQGEVRIVSSEVCNEPAGYGGSVLPGMLCAGVRSGAVDACQGDSGGPL-VQEDTRR-L 379

  Fly   322 KQVIGIVSYGLVCGSQGLPSVYTKVHLYTDWI 353
            ..|:||||:|..||....|.|||:|..|.:||
  Rat   380 WFVVGIVSWGYQCGLPNKPGVYTRVTAYRNWI 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	90/272 (33%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	88/270 (33%)
Tmprss11d	NP_001028824.2	SEA	48..150	CDD:396113
Tmprss11d	NP_001028824.2	Tryp_SPc	186..414	CDD:238113	90/272 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910