DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and c1s

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_002941253.2	Gene:	c1s / 613055	XenbaseID:	XB-GENE-995410	Length:	691	Species:	Xenopus tropicalis

Alignment Length:	363	Identity:	108/363 - (29%)
Similarity:	156/363 - (42%)	Gaps:	83/363 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 CKELTPSDCPVIFYNQHLIGAEVKY-C-DEFNDIVCCPIPLDHQNLKPAEQTRPFEKQCKQY--- 89
            |.|..|.|...:|.|....|:|:.| | ||:..:..           ||.:...:  .|..|
Frog   359 CGEPDPIDNGNVFSNTTTYGSEITYNCSDEYYALTL-----------PAGEDGTY--SCSSYGYW 410

  Fly    90 -----NEVRSACQSTPF-----------IVGGTKASGKEFPFMALIGTHRPNKSKSDINWDCGGS 138
                 |:....|  ||.           |.|||:|...:||:|...         :||... |||
Frog   411 VNSRGNKELPIC--TPVCGVHQSDKSGRIFGGTRAKPGQFPWMIQF---------TDIELG-GGS 463

  Fly   139 VVHPKFVLTAAHCLETDESKAERLDPNF--DSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHP 201
            ::..::||||||.:.      :::.|..  ...||        :.:|...:..:..:....::||
Frog   464 LISDRWVLTAAHVVN------KKIFPTMFGGVMKF--------FPNTNLQSQEKRLQAKKIIIHP 514

  Fly   202 GY-DTEDEE--QGFKNDIALVELDRKAEFNDHVAAVCLP----PDSGNDVQQVTAAGWGFTADGV 259
            .| |.||.|  ..|.||||||:|.:|.:....::.:|||    ....|:|  .|.||||.|....
Frog   515 LYQDNEDTEGQSNFDNDIALVQLTKKVKLGSCISPICLPRRGLAPVVNEV--ATIAGWGKTEKRE 577

  Fly   260 KSSHLLKVNLQRFSDEVCQK----RLRFSIDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPC 320
            .:.:|...::...|.:.|:|    :..|   |....||||...: |:||||||||:....|....
Frog   578 SAVNLQFASISLSSMDKCKKATGGKGYF---TPNMLCAGSDVGK-DSCNGDSGGPLMFTDPQDSS 638

  Fly   321 LKQVIGIVSYG-LVCGSQGLPSVYTKVHLYTDWIESIV 357
            ...:.||||:| ..||:.||   ||||..|.||||..:
Frog   639 KMYMAGIVSWGPRDCGTYGL---YTKVDNYLDWIEETI 673

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	88/267 (33%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	85/264 (32%)
c1s	XP_002941253.2	CUB	21..131	CDD:238001
		FXa_inhibition	145..173	CDD:405372
		CUB	177..288	CDD:238001
		PHA02927	301..>436	CDD:222943	20/91 (22%)
		Tryp_SPc	436..669	CDD:214473	85/265 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910