DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and tmprss9

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_021325244.1	Gene:	tmprss9 / 562051	ZFINID:	ZDB-GENE-050208-573	Length:	788	Species:	Danio rerio

Alignment Length:	371	Identity:	98/371 - (26%)
Similarity:	147/371 - (39%)	Gaps:	80/371 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PGIQILLLIASVSVVTEYCDNGTGECKELTPSDCPVIFYNQHLIGAEVKY--------------C 55
            |..|....:.||:....:.........|||.||     |...|....|.|              |
Zfish   470 PAFQENPTVPSVTTTEAHHVKAANPSSELTTSD-----YIPALGNCSVNYNCGRGMCISKINPEC 529

  Fly    56 DEFNDIVCCPIPLDHQNLKPAEQTRPFEKQCKQYNEVRSACQSTPF-----IVGGTKASGKEFPF 115
            |.   ::.||...|             ||.|.        |.:.|.     |:||..|...|:|:
Zfish   530 DR---VIDCPNEAD-------------EKNCD--------CGNRPAVTQERIIGGVTARRGEWPW 570

  Fly   116 MALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKFVVRLGELDY 180
            :..:...|.::        ||.:::|.|::||||||...|      |:|    ..:.|.||.:.:
Zfish   571 VGSLQYQRIHR--------CGATLIHCKWLLTAAHCFRGD------LNP----AGYTVSLGSVIW 617

  Fly   181 NSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEFNDHVAAVCLPPDSGNDVQ 245
            :..  .|||  ..|...:.||.:::...:.    |:||||:...|..:..:..||||....:.::
Zfish   618 SGL--GALV--IPVQRIIPHPAFNSSTMDL----DVALVEISIPAPKSYTIQTVCLPSPWHSFIK 674

  Fly   246 QVTA--AGWG-FTADGVKSSHLLKVNLQRFSDEVCQKRLRFSIDTRTQFCAGSMSSQADTCNGDS 307
            .:..  .||| ...||:.::.|.|..:.......||:.....: |....|||.|..|.|||.|||
Zfish   675 SMECYIIGWGAVREDGMITNLLQKAQVGVIDQSDCQRAYGAEL-TDNMMCAGYMEGQRDTCLGDS 738

  Fly   308 GGPIFVQHPLYPCLKQVIGIVSYGLVCGSQGLPSVYTKVHLYTDWI 353
            |||:..:..|....  :.|:.|:|..||..|.|.||.:.....:||
Zfish   739 GGPLVCRETLGRWF--LAGVTSWGHGCGRIGFPGVYMRATAVREWI 782

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	75/255 (29%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	73/253 (29%)
tmprss9	XP_021325244.1	SEA	52..146	CDD:307516
		LDLa	185..220	CDD:238060
		Tryp_SPc	232..462	CDD:238113
		LDLa	510..544	CDD:238060	9/49 (18%)
		Tryp_SPc	557..783	CDD:238113	75/255 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910