DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3700 and habp2

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001103843.2	Gene:	habp2 / 553472	ZFINID:	ZDB-GENE-030131-4721	Length:	546	Species:	Danio rerio

Alignment Length:	382	Identity:	111/382 - (29%)
Similarity:	164/382 - (42%)	Gaps:	80/382 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 YCDNGTGECKE-----------LTPSDCPVIFYNQHLIG----------AEVKYC---DEFNDIV 62
            :|..|:.:|.|           .|..:...:.:|.:||.          .|..||   |...:..
Zfish   188 FCQVGSNDCYEGNGESYRGNVSETIEEIECLPWNHNLIPYKEFEGNESIGEHNYCRNPDGDREPW 252

  Fly    63 CC-----PIPLDHQNLKPAEQTRPFEKQCK-----QYNEVRSACQS--TPFIVGGTKASGKEFPF 115
            |.     .:..::.|:||..:|.| ||...     ::::...|..|  .|.|.||.|:..:..|:
Zfish   253 CFVKEKGKLQWNYCNVKPCSETEP-EKPLTTPTKLEFSDCGKAAFSMIAPRIFGGRKSLPEAHPW 316

  Fly   116 MALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCL-ETDESKAERLDPNFDSPKFVVRLGELD 179
            .|.... ||..|.:....:|||:::...::||||||: |.||.:.|              ||.:
Zfish   317 QASFQV-RPKGSNATFEHNCGGTLIDSCWILTAAHCIDENDEVRVE--------------LGGV- 365

  Fly   180 YNSTTDDALVQDFRVVNYVVHPGY-DTEDEEQGFKNDIALVEL----DRKAEFNDHVAAVCLPPD 239
             |...||...|...|...:||..| :|.|   ...|||||::|    .|.|..:..|.|.|||.|
Zfish   366 -NLEKDDPDKQFVEVEKIIVHENYTETFD---ALYNDIALLKLKGRNGRCANESRSVRAACLPTD 426

  Fly   240 SGNDVQQVTAAGWGFTA--DGVKSSHLLKVNLQRFSDEVCQKRLRFS--IDTRTQFCAGSMSSQA 300
            ...:..:.|.:|:|.|.  .|| |:.||...:...|...|..|..:.  :|. :..|||.|..:.
Zfish   427 LFPEGTRCTISGYGATEKHHGV-STQLLDAKVLLISQSRCMSRNVYGNRMDD-SMMCAGYMQGKI 489

  Fly   301 DTCNGDSGGPIFVQHPLYPCLKQ----VIGIVSYGLVCGSQGLPSVYTKVHLYTDWI 353
            |:|.||||||:.       |.|.    :.|:||:|..||.:..|.||.:|..:.|||
Zfish   490 DSCQGDSGGPLV-------CKKDNIHYIYGVVSWGDSCGKKNKPGVYARVTKFIDWI 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	88/266 (33%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	86/264 (33%)
habp2	NP_001103843.2	EGF_CA	80..112	CDD:238011
		EGF_CA	158..190	CDD:238011	0/1 (0%)
		KR	195..273	CDD:214527	14/77 (18%)
		Tryp_SPc	302..539	CDD:214473	86/265 (32%)
		Tryp_SPc	303..542	CDD:238113	88/266 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910