DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and f2

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001015797.1	Gene:	f2 / 548514	XenbaseID:	XB-GENE-481539	Length:	607	Species:	Xenopus tropicalis

Alignment Length:	412	Identity:	108/412 - (26%)
Similarity:	154/412 - (37%)	Gaps:	122/412 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 IASVSVVTEYCDN--GTGE---C----KELTPSDCPVIFYNQHLIGAEVKYCDEFNDIVCCPIPL 68
            |..|.:...||.|  ..||   |    ..||...||            :.|||.         |:
Frog   246 IKEVKLQENYCRNPDNDGEGLWCYVSHPNLTYDYCP------------MNYCDS---------PI 289

  Fly    69 DHQNL-KPAEQTRPFEKQC----KQYNEVRSACQSTPF----------------------IVGGT 106
            |.:.| :||.:|...|.|.    |.:....:.|...|.                      ||.|.
Frog   290 DEEVLNRPAGRTTTEEHQTFFDEKSFGSGEAVCGLRPLFEQKSVEDKGEKELLESYMQGRIVKGE 354

  Fly   107 KASGKEFPFMALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKF 171
            .|.....|:..::....|.:..      ||.|::..::||:||||:             |..|
Frog   355 TAEPGSAPWQVMLFKKSPQELL------CGASLLSDRWVLSAAHCI-------------FYPP-- 398

  Fly   172 VVRLGELDYNSTTDDALV---QDFR------------VVNYVVHPGYDTEDEEQGFKNDIALVEL 221
                  .|.|.||||.||   :.||            :...:|||.|:.   ::....||||::|
Frog   399 ------WDKNYTTDDILVRIGKHFRTKYERATERIAQLERIIVHPKYNW---KENLDRDIALIQL 454

  Fly   222 DRKAEFNDHVAAVCLPPDSGNDVQQVTAA-------GWGFTAD----GVKS--SHLLKVNLQRFS 273
            .|...|::::..||||  :.:.|.::.||       |||...:    |.::  ..|.::||....
Frog   455 KRPVAFSNYIHPVCLP--TKDTVVKLLAAGYKGRVTGWGNLQETWTSGAQNLPQALQQINLPIVD 517

  Fly   274 DEVCQKRLRFSIDTRTQFCAG---SMSSQADTCNGDSGGPIFVQHPLYPCLKQVIGIVSYGLVCG 335
            .|.|:......: |...||||   ..|.:.|.|.||||||..::.|......| :||||:|..|.
Frog   518 QETCKSSTNIKV-TDNMFCAGYNPEDSKRGDACEGDSGGPFVMKDPDTGRWVQ-LGIVSWGEGCD 580

  Fly   336 SQGLPSVYTKVHLYTDWIESIV 357
            .......|..||....||...|
Frog   581 RDNKYGFYVHVHRMRKWIMKTV 602

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	81/284 (29%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	79/281 (28%)
f2	NP_001015797.1	GLA	23..86	CDD:214503
		KR	106..185	CDD:214527
		KR	206..287	CDD:214527	14/52 (27%)
		Thrombin_light	303..349	CDD:370463	5/45 (11%)
		Tryp_SPc	349..598	CDD:214473	79/282 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910