DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and AgaP_AGAP012504

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_001231011.2	Gene:	AgaP_AGAP012504 / 4578496	VectorBaseID:	AGAP012504	Length:	839	Species:	Anopheles gambiae

Alignment Length:	260	Identity:	88/260 - (33%)
Similarity:	126/260 - (48%)	Gaps:	34/260 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 GTKASGKEFPFMALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSP 169
            |:.|..:||..:|.||....::|   :.|.||||::...|:||||||...|:          :.|
Mosquito    22 GSPAYLREFAHIAAIGWTNEDQS---VRWLCGGSLIWENFILTAAHCAADDD----------NVP 73

  Fly   170 KFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEFNDHVAAV 234
            ..|.|:|:::..|..||...|..::|..:.||.:.......    ||||::|:|....:|.||..
Mosquito    74 PDVARMGDINIYSDEDDEFAQQLKIVEIIRHPKHKYNSNYY----DIALMKLERNVTLHDTVAPS 134

  Fly   235 CLPPDSGNDVQQVTAAGWGFTA-DGVKSSHLLKVNLQRFSDEVCQKRLRFSIDTRT------QFC 292
            ||..|......::.|||||.|. |...:..||||.|...:::.|....:..:....      |||
Mosquito   135 CLWLDDEIRFPELLAAGWGRTGFDQNTTKTLLKVQLAPITNDKCSTHYQRGVRKLENGLMDHQFC 199

  Fly   293 AGSMSSQADTCNGDSGGP----IFVQHPLYPCLKQVIGIVSYGLVCGSQGLPSVYTKVHLYTDWI 353
            ||  ..:.|||.||||||    :|.:..|.|.|   :|:.|:|..|| ...|.||.||..:.|||
Mosquito   200 AG--DEKMDTCPGDSGGPLHVKLFKEWKLIPFL---VGVTSFGKACG-LAAPGVYVKVSKFGDWI 258

Fly 354 353
Mosquito 259 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	88/260 (34%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	86/258 (33%)
AgaP_AGAP012504	XP_001231011.2	Tryp_SPc	22..261	CDD:238113	88/260 (34%)
		Tryp_SPc	22..258	CDD:214473	86/258 (33%)
		Trypsin	327..528	CDD:278516
		Tryp_SPc	333..>433	CDD:304450
		Tryp_SPc	611..836	CDD:304450
		Tryp_SPc	611..832	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D105391at6960
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920