DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3700 and AgaP_AGAP012269

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_001238284.2	Gene:	AgaP_AGAP012269 / 4577485	VectorBaseID:	AGAP012269	Length:	649	Species:	Anopheles gambiae

Alignment Length:	270	Identity:	84/270 - (31%)
Similarity:	120/270 - (44%)	Gaps:	43/270 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 GTKASGKEFPFMALIGTHRPNKSKSD-INWDCGGSVVHPKFVLTAAHC--LETDESKAERLDPNF 166
            |..|....:|:.|.| .||    |.| :::.||||::....:||||||  |........|:.
Mosquito    44 GIDAKPGHWPWHAAI-FHR----KGDQMDYACGGSIIDENTILTAAHCVFLVNGLLPVSRIS--- 100

  Fly   167 DSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEFNDHV 231
                  |.||.:.....::  .||:..|...:|||||::    ..|.|||||::|......::.|
Mosquito   101 ------VHLGRVHLKEVSE--FVQEHTVQELIVHPGYNS----SRFVNDIALIKLTGSITMSEFV 153

  Fly   232 AAVCL-PPDSGNDV---QQVTAAGWGFTADGVKSSHLLKVNLQRFSDEVCQK--RLRFSID-TRT 289
            ..||| ..|...::   :..|..|:|.....|.|..|.:.::.......|.|  ||.|:.. |..
Mosquito   154 QPVCLWTMDKNQELIVGKTGTLVGFGLNEQDVVSEQLKQASIGVVDALTCIKSDRLSFANQLTAE 218

  Fly   290 QFCAGSMSSQADTCNGDSGGPIF--VQHPLYPCLKQVIGIVSYGLVCGSQGL--PSVYT---KVH 347
            .||.|..|: ...|||||||.:|  |:...:     |.|:||:..|....||  ||.||   .|.
Mosquito   219 MFCGGGQSN-VSACNGDSGGGLFFNVEGKWF-----VRGVVSFIPVRQRTGLCDPSKYTAYADVA 277

  Fly   348 LYTDWIESIV 357
            .|..||:..:
Mosquito   278 KYLGWIDQYI 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	84/267 (31%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	82/264 (31%)
AgaP_AGAP012269	XP_001238284.2	Tryp_SPc	41..285	CDD:238113	84/266 (32%)
		Tryp_SPc	43..283	CDD:214473	82/264 (31%)
		Tryp_SPc	418..636	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910