DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and ndl

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_523947.2	Gene:	ndl / 38738	FlyBaseID:	FBgn0002926	Length:	2616	Species:	Drosophila melanogaster

Alignment Length:	303	Identity:	84/303 - (27%)
Similarity:	133/303 - (43%)	Gaps:	49/303 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 CPIPLDHQNLKPAEQTRPFEKQCKQ-YNEVRSACQSTPFIVGGTKASGKEFPFMALIGTHRPNKS 127
            |.:|.....|:.:::.|......|: ..:.|        ||||:..|..::||:..|  :|..|
  Fly  1114 CGLPSKSSMLEHSKRVRRAVSDSKEIVGDGR--------IVGGSYTSALQWPFVVAI--YRNGK- 1167

  Fly   128 KSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKFVVRLGELDYNSTTDDALVQDF 192
                 :.|||::...:::::||||:           .|:....:.||.|.|..:|.:....:|.
  Fly  1168 -----FHCGGTIYSDRWIISAAHCV-----------INYGKYFYEVRAGLLRRSSYSPATQIQP- 1215

  Fly   193 RVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEFNDHVAAVCLPPDS----GND-----VQQV- 247
             |.:.|||..|    |.:..:||::|:.|....:||..|..:|||...    |:|     |:..
  Fly  1216 -VSHVVVHQAY----ERRSMRNDLSLLRLLNPLQFNRWVKPICLPDKGRTTVGDDWIWGPVEHTL 1275

  Fly   248 -TAAGWGFTADGVKSSHLLKVNLQRFSDEVCQKRLRFSIDTRTQFCAGSMSSQADTCNGDSGGPI 311
             |..|||...:...||..::..:.....:......:.|.|    .|||......|.|.||||||:
  Fly  1276 CTVVGWGAIREKGPSSDPMRQVIVPIRKKCTDPEDQASED----ICAGDPDGGRDACQGDSGGPL 1336

  Fly   312 FVQHPLYPCLKQVIGIVSYGLVCGSQGLPSVYTKVHLYTDWIE 354
            |.:....|....:.|:||:|..|.......|||:|.||.||:|
  Fly  1337 FCRSVSNPDEFYLAGVVSHGNGCARPQEFGVYTRVTLYLDWLE 1379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	78/264 (30%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	76/261 (29%)
ndl	NP_523947.2	LDLa	891..927	CDD:238060
		Tryp_SPc	1144..1377	CDD:214473	76/269 (28%)
		Tryp_SPc	1145..1379	CDD:238113	77/262 (29%)
		LDLa	1399..1430	CDD:238060
		Metaviral_G	1448..1600	CDD:118131
		LDLa	1710..1743	CDD:238060
		LDLa	1776..1811	CDD:238060
		DUF1986	2041..2158	CDD:286432
		LDLa	2309..2339	CDD:197566
		LDLa	2350..2383	CDD:197566
		LDLa	2421..2457	CDD:238060
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100