DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3700 and KLK2

DIOPT Version :9

Sequence 1:NP_611736.1 Gene:CG3700 / 37640 FlyBaseID:FBgn0034796 Length:360 Species:Drosophila melanogaster
Sequence 2:NP_005542.1 Gene:KLK2 / 3817 HGNCID:6363 Length:261 Species:Homo sapiens


Alignment Length:279 Identity:80/279 - (28%)
Similarity:116/279 - (41%) Gaps:63/279 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   102 IVGGTKASGKEFPFMALIGTHRPNKSKSDINW-DCGGSVVHPKFVLTAAHCLETDESKAERLDPN 165
            ||||.:......|:...:.:|         .| .|||.:|||::||||||||:.:..        
Human    25 IVGGWECEKHSQPWQVAVYSH---------GWAHCGGVLVHPQWVLTAAHCLKKNSQ-------- 72

  Fly   166 FDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTE---------DEEQGFKNDIALVEL 221
                   |.||.  :|....:...|...|.:...||.|:..         ||:.  .:|:.|:.|
Human    73 -------VWLGR--HNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDS--SHDLMLLRL 126

  Fly   222 DRKAEFNDHVAAVCLP---PDSGNDVQQVTAAGWGFTADGVKSSHLLK------VNLQRFSDEVC 277
            ...|:..|.|..:.||   |..|....   |:|||    .::....|:      |:|...|:::|
Human   127 SEPAKITDVVKVLGLPTQEPALGTTCY---ASGWG----SIEPEEFLRPRSLQCVSLHLLSNDMC 184

  Fly   278 QKRLRFSIDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQVIGIVSYG-LVCGSQGLPS 341
            .:.....: |....|||..:...|||.||||||:.       |...:.||.|:| ..|.....|:
Human   185 ARAYSEKV-TEFMLCAGLWTGGKDTCGGDSGGPLV-------CNGVLQGITSWGPEPCALPEKPA 241

  Fly   342 VYTKVHLYTDWIESIVWGN 360
            |||||..|..||:..:..|
Human   242 VYTKVVHYRKWIKDTIAAN 260

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3700NP_611736.1 Tryp_SPc 102..356 CDD:238113 79/273 (29%)
Tryp_SPc 102..353 CDD:214473 77/270 (29%)
KLK2NP_005542.1 Tryp_SPc 25..256 CDD:238113 79/273 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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