DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and Tmprss4

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_038937788.1	Gene:	Tmprss4 / 367074	RGDID:	1305033	Length:	478	Species:	Rattus norvegicus

Alignment Length:	373	Identity:	102/373 - (27%)
Similarity:	153/373 - (41%)	Gaps:	61/373 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PGIQILL---------LIASVSVVTEYC-DNGTGECKELTPSDCPVIFYNQHLIGAEVKYCDEFN 59
            ||:.:.|         |.|:.......| ||.|   :.|..:.|..:.||.......|:.... .
  Rat   141 PGVTVRLSKDRSTLQVLDAARGTWASVCFDNFT---EALAKTACRQMGYNSQPAFGPVEMGPN-Q 201

  Fly    60 DIVCCPIPLDHQNLKPAEQTRPFEKQCKQYNEVRSAC------QSTPFIVGGTKASGKEFPFMAL 118
            .::..|:..:.|.|    |.:...:.|...:.|...|      ..|..:|||.:||...:|:...
  Rat   202 TLLVTPVTGNSQEL----QMQNGSRSCLSGSLVSLRCLDCGKSLKTTRVVGGVEASADSWPWQVS 262

  Fly   119 IGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKFVVRLGELDYNST 183
            |..::.:.        ||||::...::||||||..          ...|...:.||.|.....::
  Rat   263 IQYNKQHV--------CGGSILDHHWILTAAHCFR----------KYLDVSSWKVRAGSNKLGNS 309

  Fly   184 TDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEFNDHVAAVCLP--PDSGNDVQQ 246
            ....:.:.|     :..|     :..|..:.|||||:|.....|:..|..:|||  .:.......
  Rat   310 PSLPVAKIF-----IAEP-----NPLQPKEKDIALVKLKMPLTFSGSVRPICLPFSDEELIPTMP 364

  Fly   247 VTAAGWGFTAD--GVKSSHLLKVNLQRFSDEVCQKRLRFSID-TRTQFCAGSMSSQADTCNGDSG 308
            |...|||||.:  |..|..||:.::|......|.....:..: |....|||:.....|||.||||
  Rat   365 VWVIGWGFTEENGGKMSDTLLQASVQVIDSARCNAEDAYQGEVTAGMLCAGTPQGGKDTCQGDSG 429

  Fly   309 GPIFVQHPLYPCLKQVIGIVSYGLVCGSQGLPSVYTKVHLYTDWIESI 356
            ||:...:..:    ||:||||:|..|||...|.|||||..|.|||.::
  Rat   430 GPLMYHYDKW----QVVGIVSWGYGCGSPSTPGVYTKVTAYLDWIYNV 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	80/258 (31%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	78/255 (31%)
Tmprss4	XP_038937788.1	LDLa	99..133	CDD:238060
		SRCR_2	149..238	CDD:413346	18/96 (19%)
		Tryp_SPc	245..470	CDD:214473	78/256 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910