DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and Tmprss11b

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001004020.1	Gene:	Tmprss11b / 365265	RGDID:	1303278	Length:	420	Species:	Rattus norvegicus

Alignment Length:	270	Identity:	84/270 - (31%)
Similarity:	121/270 - (44%)	Gaps:	58/270 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 IVGGTKASGKEFPFMALI---GTHRPNKSKSDINWDCGGSVVHPKFVLTAAHC-LETDESKAERL 162
            |.||:.|...|:|:.|.:   |.|.           ||.|::..:|:|||||| |.|
  Rat   189 ITGGSTAQKGEWPWQASLRVNGKHH-----------CGASLIGERFLLTAAHCFLRT-------- 234

  Fly   163 DPNFDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQG-FKNDIALVELDRKAE 226
                ::||.:.    :.:.:....|.:|.: |...::|     ||..:| ..:|:|:::|..|..
  Rat   235 ----NNPKNLT----VSFGTRVTPAYMQHY-VEEVIIH-----EDYVKGQHHDDVAIIKLTEKVS 285

  Fly   227 FNDHVAAVCL-------PPDSGNDVQQVTAAGWGFTADGVKSSHLL-KVNLQRFSDEVCQKRLRF 283
            |.:.|..|||       ||..|     |...|||..:...||..|| |.:::......|.....:
  Rat   286 FRNDVHRVCLPEATQVFPPGEG-----VVVTGWGSLSYNGKSPLLLQKASIKIIDTNACNSEEAY 345

  Fly   284 S---IDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQVIGIVSYGLVCGSQGLPSVYTK 345
            .   :|  |..|||.|....|.|.||||||:.  ||....:..::||||:|..||....|.||.:
  Rat   346 GGRIMD--TMLCAGYMEGYVDACQGDSGGPLV--HPNSRDIWYLVGIVSWGHECGRVNKPGVYMR 406

  Fly   346 VHLYTDWIES 355
            |..|.|||.|
  Rat   407 VTSYRDWIAS 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	84/270 (31%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	81/266 (30%)
Tmprss11b	NP_001004020.1	SEA	50..144	CDD:279699
		Tryp_SPc	188..414	CDD:214473	81/266 (30%)
		Tryp_SPc	189..417	CDD:238113	84/270 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910