DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3700 and Prss53

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	269	Identity:	66/269 - (24%)
Similarity:	105/269 - (39%)	Gaps:	66/269 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 EFPFMALI---GTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLE---TDESKAERLDPNFDSPK 170
            |:|:.|.:   |.|           .|.||:|...:|||||||.|   |.|..:
Mouse    47 EWPWQASVRRQGVH-----------ICSGSLVADTWVLTAAHCFEKMATAELSS----------- 89

  Fly   171 FVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEFNDHVAAVC 235
            :.|.||.|.....:..|  ::..|....:...|:  ...||  :|:||::|.....    ...:|
Mouse    90 WSVVLGSLKQEGQSPGA--EEVGVAALQLPKAYN--HYSQG--SDLALLQLTHPTV----QTTLC 144

  Fly   236 LPPDSGNDVQQVT----------AAGWGFTADGVKSSHLLKVNLQRFSDEVC-------QKRLRF 283
            ||        |.|          |.||......| |..|..:.|:..|...|       .:||..
Mouse   145 LP--------QPTYHFPFGASCWATGWDQNTSDV-SRTLRNLRLRLISRPTCNCLYNRLHQRLLS 200

  Fly   284 SIDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQVIGIVSYGLVCGSQGLPSVYTKVHL 348
            :.......|.|:...:...|.||||||:..:.|....::  :||:|:...|..:..|.:.|.:.:
Mouse   201 NPARPGMLCGGAQPGEQGPCQGDSGGPVMCREPDGHWVQ--VGIISFTSKCAQEDTPVLLTDMAV 263

  Fly   349 YTDWIESIV 357
            ::.|:::.|
Mouse   264 HSSWLQAHV 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	65/266 (24%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	64/263 (24%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46
		Tryp_SPc	45..271	CDD:238113	65/266 (24%)
		Tryp_SPc	311..522	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910