DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and CLIPC1

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_552698.3	Gene:	CLIPC1 / 3291827	VectorBaseID:	AGAP008835	Length:	389	Species:	Anopheles gambiae

Alignment Length:	400	Identity:	139/400 - (34%)
Similarity:	197/400 - (49%)	Gaps:	76/400 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ILLLIASVSVVTEYCD-------NGTGECKELTPSDC-PVIFYNQHLIGAEVK--YCDEFNDIVC 63
            ||.:||:|....|..|       |..|.|:.:  |:| |||...::..|...|  :.|.. .|||
Mosquito    16 ILFVIATVRCDLEVGDPCIVQRTNEPGICRIV--SECAPVIDDIRNRRGNPTKCGFIDRV-QIVC 77

  Fly    64 CPIPLDHQNLKPAEQTRP----------FEKQCKQYNE-------VRSACQSTP----------- 100
            ||    .....||..|.|          ..::|.:|.:       |.|...|.|
Mosquito    78 CP----QVGTTPAAATTPSTTPRNEHQRVAEKCAEYGQAVFSKEYVNSLTASEPKLQTIDKCGHT 138

  Fly   101 ---FIVGGTKASGKEFPFMALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERL 162
               .||.|..|..:|||.|||||.    ....:|.:.||||:|..:|:|||.|||.:
Mosquito   139 AVELIVDGELAKAREFPHMALIGF----GEAPEIRYLCGGSLVSDRFILTAGHCLTS-------- 191

  Fly   163 DPNFDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEF 227
             .|| .|..:||||||...|:||:|..:|:.:...:.||.|    ::....|||||::|:||..|
Mosquito   192 -TNF-GPATIVRLGELSLASSTDEAFPEDYDIAERIPHPEY----KQTSHYNDIALIKLNRKVIF 250

  Fly   228 NDHVAAVCLPPDSGNDVQQVTAAGWGFTADGV-KSSHLLKVNLQRFSDEVCQ------KRLRFSI 285
            :.:...:|||..:....::..|.|||....|: :||.||||.|..|..|.|:      ::||..:
Mosquito   251 SPYARPICLPLQAAIPQKRAIATGWGAIGFGLEQSSALLKVTLDMFRFEECKDQFEPTRKLRTGL 315

  Fly   286 DTRTQFCAGSMSSQADTCNGDSGGPIFVQHP--LYPCLKQVIGIVSYGLVCGSQGLPSVYTKVHL 348
            :..||.||||.:|..|||.||||||:.|.:.  :| |...:||:.|:|..||..|:|:|||.|:.
Mosquito   316 NATTQLCAGSRNSTKDTCQGDSGGPLQVYNDANVY-CTYTIIGVTSFGQNCGLAGVPAVYTTVYS 379

  Fly   349 YTDWIESIVW 358
            |..|||::::
Mosquito   380 YLSWIENLIF 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	106/262 (40%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	103/259 (40%)
CLIPC1	XP_552698.3	CLIP	39..79	CDD:197829	14/42 (33%)
		Tryp_SPc	143..386	CDD:238113	105/261 (40%)
		Tryp_SPc	143..384	CDD:214473	103/259 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D105391at6960
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920