DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3700 and Tmprss11b

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_795998.2	Gene:	Tmprss11b / 319875	MGIID:	2442893	Length:	416	Species:	Mus musculus

Alignment Length:	269	Identity:	80/269 - (29%)
Similarity:	120/269 - (44%)	Gaps:	56/269 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 IVGGTKASGKEFPFMALI---GTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLD 163
            |.||:.|...|:|:.|.:   |.|.           ||.|::..:|:||||||.:
Mouse   185 ITGGSTAHKGEWPWQASLRVNGKHY-----------CGASLIGERFLLTAAHCFQ---------- 228

  Fly   164 PNFDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQG-FKNDIALVELDRKAEF 227
             ..::||.:.    :.:.:....|.:| ..|...::|     ||..:| ..:|:|:::|..|..|
Mouse   229 -GTNNPKNLT----VSFGTRVTPAYMQ-HSVQEIIIH-----EDYVKGEHHDDVAVIKLTEKVSF 282

  Fly   228 NDHVAAVCL-------PPDSGNDVQQVTAAGWG-FTADGVKSSHLLKVNLQRFSDEVCQKRLRFS 284
            |:.|..|||       ||..|     |...||| |:.:|.....|.|.:::......|.....:.
Mouse   283 NNDVHRVCLPESTQIFPPGEG-----VVVTGWGSFSYNGKSPLLLQKASIKIIDTNTCNSEEAYG 342

  Fly   285 ---IDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQVIGIVSYGLVCGSQGLPSVYTKV 346
               :|  |..|||.:....|.|.||||||:.  ||....:..::||||:|..||....|.||.:|
Mouse   343 GRIVD--TMLCAGYLEGSIDACQGDSGGPLV--HPNSRDIWYLVGIVSWGHECGRVNKPGVYMRV 403

  Fly   347 HLYTDWIES 355
            ..|.:||.|
Mouse   404 TSYRNWIAS 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	80/269 (30%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	77/265 (29%)
Tmprss11b	NP_795998.2	SEA	46..140	CDD:279699
		Tryp_SPc	184..410	CDD:214473	77/265 (29%)
		Tryp_SPc	185..413	CDD:238113	80/269 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910