DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3700 and Tmprss3

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_038954650.1	Gene:	Tmprss3 / 309665	RGDID:	1310135	Length:	454	Species:	Rattus norvegicus

Alignment Length:	275	Identity:	81/275 - (29%)
Similarity:	128/275 - (46%)	Gaps:	50/275 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 SACQS----TPFIVGGTKASGKEFPFMALI---GTHRPNKSKSDINWDCGGSVVHPKFVLTAAHC 151
            |||..    :|.||||..:|..::|:...:   |.|.           |||||:.|.:::|||||
  Rat   205 SACGMRTGYSPRIVGGNVSSLTQWPWQVSLQFQGYHL-----------CGGSVITPLWIVTAAHC 258

  Fly   152 LETDESKAERLDPNFD--SPK-FVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFK 213
            :             :|  .|| :.|::|.:    :..|:.|....|...:.|..|    :.:...
  Rat   259 V-------------YDLYHPKSWTVQVGLV----SLMDSPVPSHLVEKIIYHSKY----KPKRLG 302

  Fly   214 NDIALVELDRKAEFNDHVAAVCLPPDSGN--DVQQVTAAGWGFTADGV--KSSHLLKVNLQRFSD 274
            |||||::|.....|::.:..:|||....|  |.:....:|||.|.||.  .|..|....:...|:
  Rat   303 NDIALMKLSEPLTFDETIQPICLPNSEENFPDGKLCWTSGWGATEDGAGDASPVLNHAAVPLISN 367

  Fly   275 EVCQKR-LRFSIDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQVIGIVSYGLVCGSQG 338
            ::|..| :...|.:.:..|||.:....|:|.||||||:..|...   |.:::|..|:|:.|....
  Rat   368 KICNHRDVYGGIISPSMLCAGYLKGGVDSCQGDSGGPLVCQERR---LWKLVGATSFGIGCAEVN 429

  Fly   339 LPSVYTKVHLYTDWI 353
            .|.|||::..:.|||
  Rat   430 KPGVYTRITSFLDWI 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	77/263 (29%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	75/261 (29%)
Tmprss3	XP_038954650.1	LDLa	74..107	CDD:238060
		SRCR_2	112..211	CDD:406055	3/5 (60%)
		Tryp_SPc	216..444	CDD:214473	75/262 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910