DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and F12

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001014028.1	Gene:	F12 / 306761	RGDID:	1359175	Length:	603	Species:	Rattus norvegicus

Alignment Length:	357	Identity:	94/357 - (26%)
Similarity:	140/357 - (39%)	Gaps:	102/357 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 YCDEFNDIVCCPIPL--------DHQNLKPAEQTRPFEKQCKQY--------------------- 89
            ||    |:..|.:|.        .|..|||    ||...|..|:
  Rat   288 YC----DLEQCQMPTLTSPVSPESHDMLKP----RPPILQMPQFPSLSDALDNSTRNQNVVSRTS 344

  Fly    90 -----NEVRSACQSTPFIVGGTKASGKEFPFMALIGTHRPNKSKSDINWD---CGGSVVHPKFVL 146
                 ...|....|...:|||..|.....|::|.            :.|.   |.||::.|.:||
  Rat   345 TVVCGQRFRKRLSSLRRVVGGLVALPGSHPYIAA------------LYWGDSFCAGSLIDPCWVL 397

  Fly   147 TAAHCLETDESKAERLDPNFDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQG 211
            ||||||:...:..|          ..|.||:..:|.:.:..  |...|.:|.:|.|:.::.
  Rat   398 TAAHCLQKRPAPEE----------LTVVLGQDRHNQSCERC--QTLAVHSYRLHEGFSSKT---- 446

  Fly   212 FKNDIALVEL-DRK---AEFNDHVAAVCLPPDSGNDVQQV--TAAGWGFTADG-------VKSSH 263
            :::|:||:.| .||   |..:.||..||||..:....:.|  ..||||...:|       ::.:.
  Rat   447 YQHDLALLRLRGRKNSCAILSPHVQPVCLPSSAAPPSETVLCEVAGWGHQFEGAEEYATFLQEAQ 511

  Fly   264 LLKVNLQRFS------DEVCQKRLRFSIDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLK 322
            :..::|.|.|      |.:....|          |||.:...||.|.||||||:.....:.....
  Rat   512 VPFISLDRCSSSNVHGDAILPGML----------CAGFLEGGADACQGDSGGPLVCDEGVTERQL 566

  Fly   323 QVIGIVSYGLVCGSQGLPSVYTKVHLYTDWIE 354
            .:.|::|:|..||.:..|.|||.|..|.|||:
  Rat   567 TLRGVISWGSGCGDRNKPGVYTDVANYLDWIQ 598

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	79/275 (29%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	77/272 (28%)
F12	NP_001014028.1	FN2	40..87	CDD:238019
		EGF_CA	95..130	CDD:238011
		FN1	132..170	CDD:238018
		EGF	177..207	CDD:278437
		Kringle	216..294	CDD:278480	3/9 (33%)
		Tryp_SPc	361..597	CDD:214473	77/273 (28%)
		Tryp_SPc	362..600	CDD:238113	79/275 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910