DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3700 and Tmprss13

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001121000.1	Gene:	Tmprss13 / 300682	RGDID:	1310872	Length:	539	Species:	Rattus norvegicus

Alignment Length:	384	Identity:	95/384 - (24%)
Similarity:	148/384 - (38%)	Gaps:	93/384 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 CDNGTGECKELTPSD---CPVIFYNQHLI-------GAEVKYC-DEFNDI----VCCPIPLD--H 70
            || |..:||  ..||   |....:::.|:       |..:..| ..:||.    .|..:..|  :
  Rat   183 CD-GVVDCK--MKSDELGCVRFDWDKSLLKVYSGSSGEWLPVCSSSWNDTDSERTCQQLGFDSAY 244

  Fly    71 QNLKPAEQTRPFEKQCKQYNE------VRSACQS----------------TPFIVGGTKASGKEF 113
            :..:.|.:.........:||.      .||.|.|                |..||||...|..::
  Rat   245 RTTEVAHRDVTSSFLLSEYNSTIQESLTRSECPSRRYVSLQCAHCGLRAMTGRIVGGALTSESKW 309

  Fly   114 PFMALI---GTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKFVVRL 175
            |:...:   .||           .|||:::..::|||||||.                  ||.|.
  Rat   310 PWQVSLHFGTTH-----------ICGGTLIDAQWVLTAAHCF------------------FVTRE 345

  Fly   176 GELD----YNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEFNDHVAAVCL 236
            ..|:    |..|::...:.:...::.::..|..|::::.   .|||||.|.:....:.|:...||
  Rat   346 KILEGWKVYAGTSNLHQLPEAASISQIIINGNYTDEQDD---YDIALVRLSKPLTLSAHIHPACL 407

  Fly   237 PPDSG----NDVQQVTAAGWGFTADGVKSSHLLKVNLQRFSDEVCQKRLRF-SIDTRTQFCAGSM 296
            |....    |:...:|..|.....|...|..|.:|.:.....:.|...|.: |..|....|||.:
  Rat   408 PLHGQTFGLNETCWITGFGKTKETDEKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDL 472

  Fly   297 SSQADTCNGDSGGPIFVQ--HPLYPCLKQVIGIVSYGLVCGSQGLPSVYTKVHLYTDWI 353
            ....|:|.||||||:..:  :..|     :.|:.|:|..||.:..|.|||||.....||
  Rat   473 RGGRDSCQGDSGGPLVCEQNNRWY-----LAGVTSWGTGCGQKNKPGVYTKVTEVLPWI 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	72/266 (27%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	70/264 (27%)
Tmprss13	NP_001121000.1	WWbp	<1..69	CDD:304964
		SRCR_2	203..292	CDD:292133	14/88 (16%)
		SRCR	216..288	CDD:278931	13/71 (18%)
		Tryp_SPc	297..526	CDD:214473	70/265 (26%)
		Tryp_SPc	298..526	CDD:238113	70/264 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910