DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3700 and GZMA

DIOPT Version :9

Sequence 1:NP_611736.1 Gene:CG3700 / 37640 FlyBaseID:FBgn0034796 Length:360 Species:Drosophila melanogaster
Sequence 2:NP_006135.2 Gene:GZMA / 3001 HGNCID:4708 Length:262 Species:Homo sapiens


Alignment Length:270 Identity:80/270 - (29%)
Similarity:119/270 - (44%) Gaps:50/270 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   102 IVGGTKASGKEFPFMALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNF 166
            |:||.:.:....|:|.|:...|..        .|.|:::...:|||||||             |.
Human    29 IIGGNEVTPHSRPYMVLLSLDRKT--------ICAGALIAKDWVLTAAHC-------------NL 72

  Fly   167 DSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEFNDHV 231
            :....|: ||.  ::.|.::...|...|.....:|.||....|    .|:.|::|..||:.|.:|
Human    73 NKRSQVI-LGA--HSITREEPTKQIMLVKKEFPYPCYDPATRE----GDLKLLQLMEKAKINKYV 130

  Fly   232 AAVCLPPDSGNDVQQVT---AAGWGFTADGVK-SSHLLKVNLQRFSDEVCQKRLRFSIDT---RT 289
            ..:.| |..|:||:..|   .||||.|.:... |..|.:||:.....:||..|..::.:.   ..
Human   131 TILHL-PKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMN 194

  Fly   290 QFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQVIGIVSYGL--VCGSQGLPSVY---TKVHLY 349
            ..||||:....|:||||||.|:.       |.....|:.|:||  .||....|.||   :|.|| 
Human   195 MVCAGSLRGGRDSCNGDSGSPLL-------CEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHL- 251

  Fly   350 TDWIESIVWG 359
             :||...:.|
Human   252 -NWIIMTIKG 260

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3700NP_611736.1 Tryp_SPc 102..356 CDD:238113 79/265 (30%)
Tryp_SPc 102..353 CDD:214473 77/262 (29%)
GZMANP_006135.2 Tryp_SPc 29..254 CDD:238113 77/262 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D476534at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.010

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