Protein Alignment CG3700 and GZMH

DIOPT Version :9

• Sequence 1: NP_611736.1
• Gene: CG3700 / 37640
• FlyBaseID: FBgn0034796
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: NP_219491.1
• Gene: GZMH / 2999
• HGNCID: 4710
• Length: 246
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 75/258 - (29%)
• Similarity: 108/258 - (41%)
• Gaps: 37/258 - (14%)

  Fly    99 TPFIVGGTKASGKEFPFMALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLD 163
            |..|:||.:|.....|:||.:...:....|.     |||.:|...||||||||
Human    18 TEEIIGGHEAKPHSRPYMAFVQFLQEKSRKR-----CGGILVRKDFVLTAAHC------------ 65

  Fly   164 PNFDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEFN 228
               ......|.||.  :|....:...|...|...:.||.|:.::    |.|||.|::|:|||::.
Human    66 ---QGSSINVTLGA--HNIKEQERTQQFIPVKRPIPHPAYNPKN----FSNDIMLLQLERKAKWT 121

  Fly   229 DHVAAVCLPPDSG--NDVQQVTAAGWGFTADGVKSSHLLKVNLQRFSDEVCQKRLRFSIDTRTQF 291
            ..|..:.||....  ...|..:.||||:.:....::.|.:|.|....|..|::....:....|:.
Human   122 TAVRPLRLPSSKAQVKPGQLCSVAGWGYVSMSTLATTLQEVLLTVQKDCQCERLFHGNYSRATEI 186

  Fly   292 CAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQVIGIVSYGLVCGSQGLPSVYTKVHLYTDWIE 354
            |.|..........||||||:.       |.....||:|||...|:.  |.||.||..:..||:
Human   187 CVGDPKKTQTGFKGDSGGPLV-------CKDVAQGILSYGNKKGTP--PGVYIKVSHFLPWIK 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	74/255 (29%)
		Tryp_SPc	102..353	CDD:214473	72/252 (29%)
GZMH	NP_219491.1	Tryp_SPc	21..242	CDD:238113	74/255 (29%)
		Mediates the preference for acidic residues at the P3' and P4' sites	46..48		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910