DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and Tmprss15

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_038944148.1	Gene:	Tmprss15 / 288291	RGDID:	1311046	Length:	1028	Species:	Rattus norvegicus

Alignment Length:	389	Identity:	96/389 - (24%)
Similarity:	166/389 - (42%)	Gaps:	83/389 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 EYCDNGTGE--CKEL---TPSDCPVIFYNQH---LIGAEVKYCDEFNDIVCCPIPLDHQNLK-PA 76
            ::|.:|:.|  |...   |.|:..::.:|.|   .|.....:..:.::.||..:.|...|.. |.
  Rat   670 QHCSDGSDEAHCVRFLNGTQSNNGLVQFNIHNIWHIACAEPWTTQISNEVCHLLGLGSANSSMPI 734

  Fly    77 EQT--RPFEK---------------QCKQYNEVRSACQST------------PFIVGGTKASGKE 112
            ..|  .||.:               ||.|.:.:...|...            |.||||:......
  Rat   735 LSTGGGPFVRLNEAPNGSLILTPSLQCSQDSLILLQCNHKSCGEKMVTQKVGPKIVGGSDTQAGA 799

  Fly   113 FPFMALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKFVVRLGE 177
            :|::..:    ..:.:|.....||.|:|...::::||||:         ...|.|..::...||.
  Rat   800 WPWVVAL----YYRDRSGDRLLCGASLVSSDWLVSAAHCV---------YRRNLDPTRWTAVLGL 851

  Fly   178 LDYNSTTDDALVQDFRVVN-YVVHPGYDTEDEEQGFKNDIALVELDRKAEFNDHVAAVCLPPDSG 241
            ...::.|...:|:  |||: .|::|.||...:    .||||::.|:.|..:.|::..:|||.::.
  Rat   852 HMQSNLTSPQVVR--RVVDRIVINPHYDKRRK----VNDIAMMHLEFKVNYTDYIQPICLPEENQ 910

  Fly   242 NDV--QQVTAAGWGF-------TADGVKSSHLLKVNLQRFSDEVCQKRLRFSIDTRTQFCAGSMS 297
            ...  :..:.||||:       |.|.:|.:.:..|     |:|.||::|.....|.:..|||...
  Rat   911 TFTPGRMCSIAGWGYNKINAGSTVDVLKEADVPLV-----SNEKCQQQLPEYDITESMLCAGYEE 970

  Fly   298 SQADTCNGDSGGPIFVQHPLYPCLKQ----VIGIVSYGLVCGSQGLPSVYTKVHLYTDWIESIV 357
            ...|:|.||||||:.       |.:.    ::|:.|:|:.|.....|.||.:|..:.:||.|.:
  Rat   971 GGTDSCQGDSGGPLM-------CQENNRWFLVGVTSFGVQCALPNHPGVYARVSQFIEWIHSFL 1027

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	73/267 (27%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	71/264 (27%)
Tmprss15	XP_038944148.1	SEA	54..155	CDD:214554
		LDLa	188..221	CDD:238060
		CUB	229..335	CDD:412131
		MAM	351..507	CDD:395504
		CUB	528..635	CDD:395345
		LDLa	647..681	CDD:238060	3/10 (30%)
		Tryp_SPc	789..1025	CDD:238113	73/266 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910