DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and F7

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_690059.1	Gene:	F7 / 260320	RGDID:	628678	Length:	446	Species:	Rattus norvegicus

Alignment Length:	380	Identity:	110/380 - (28%)
Similarity:	154/380 - (40%)	Gaps:	96/380 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 CDNGTGECKELTPS---DCPVIF--------YNQHLIGA-EVKYCDEFNDIVCCPIPLDHQNLKP 75
            |.|| |.|::...|   .||:.|        .|:.||.| |...||::     |   .||...|
  Rat    96 CQNG-GTCQDHLKSYVCFCPLDFEGRNCEKNKNEQLICANENGDCDQY-----C---RDHVGTK- 150

  Fly    76 AEQT---------RPFEKQCKQYNEVRSACQSTPF------------IVGGTKASGKEFPFMALI 119
              :|         :|.|..||.  :|...|...|.            ||||......|.|:.|::
  Rat   151 --RTCSCHEDYVLQPDEVSCKP--KVEYPCGRIPVVEKRNFSRPQGRIVGGYVCPKGECPWQAVL 211

  Fly   120 GTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKF------VVRLGEL 178
                    |.:....||..::..::::|||||              ||  ||      .|.|||.
  Rat   212 --------KFNEALLCGAVLLDTRWIVTAAHC--------------FD--KFGKLVNITVVLGEH 252

  Fly   179 DYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEFNDHVAAVCLPPD--SG 241
            |::....   .:..|:|..|:.|...|.....   :|||||.|.|...|.|:|..:|||..  |.
  Rat   253 DFSEKEG---TEQVRLVEQVIMPNKYTRGRTD---HDIALVRLHRPVTFTDYVVPLCLPERAFSE 311

  Fly   242 NDVQQV---TAAGWGFTAD-GVKSSHLLKVNLQRFSDEVCQKRLRFSID----TRTQFCAGSMSS 298
            |.:..:   ..:|||...| |..:..|:.:.:.|...:.|.:..:.|.:    |...||||.|..
  Rat   312 NTLASIRFSRVSGWGQLLDRGATALELMVIEVPRLMTQDCLEHAKHSANTPRITENMFCAGYMDG 376

  Fly   299 QADTCNGDSGGPIFVQHPLYPCLKQVIGIVSYGLVCGSQGLPSVYTKVHLYTDWI 353
            ..|.|.|||||| ...|  |.....:.|:||:|..|.:.|...|||:|..|.||:
  Rat   377 TKDACKGDSGGP-HATH--YHGTWYLTGVVSWGEGCAAIGHIGVYTRVSQYIDWL 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	82/268 (31%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	81/266 (30%)
F7	NP_690059.1	GLA	25..85	CDD:214503
		EGF_CA	87..123	CDD:238011	9/27 (33%)
		Tryp_SPc	194..430	CDD:238113	82/268 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000