DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and F11

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_005262878.1	Gene:	F11 / 2160	HGNCID:	3529	Length:	626	Species:	Homo sapiens

Alignment Length:	273	Identity:	86/273 - (31%)
Similarity:	128/273 - (46%)	Gaps:	33/273 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 CKQYNEVRSACQSTPFIVGGTKASGKEFPFMALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAH 150
            ||..||..:..:  |.|||||.:...|:|:...:.|..|.:...     ||||::..:::|||||
Human   375 CKMDNECTTKIK--PRIVGGTASVRGEWPWQVTLHTTSPTQRHL-----CGGSIIGNQWILTAAH 432

  Fly   151 CLETDESKAERLDPNFDSPKFV-VRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKN 214
            |..           ..:|||.: |..|.|:.:...:|  ...|.|...::|..|  :..|.|:
Human   433 CFY-----------GVESPKILRVYSGILNQSEIKED--TSFFGVQEIIIHDQY--KMAESGY-- 480

  Fly   215 DIALVELDRKAEFNDHVAAVCLPPDSGNDV--QQVTAAGWGF--TADGVKSSHLLKVNLQRFSDE 275
            ||||::|:....:.|....:|||.....:|  ......|||:  ..|.:::: |.|..:...::|
Human   481 DIALLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNT-LQKAKIPLVTNE 544

  Fly   276 VCQKRLRFSIDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQVIGIVSYGLVCGSQGLP 340
            .||||.|....|....|||......|.|.||||||:..:|..   :..::||.|:|..|..:..|
Human   545 ECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNE---VWHLVGITSWGEGCAQRERP 606

  Fly   341 SVYTKVHLYTDWI 353
            .|||.|..|.|||
Human   607 GVYTNVVEYVDWI 619

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	81/257 (32%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	79/255 (31%)
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519	86/273 (32%)
		Tryp_SPc	388..619	CDD:214473	79/256 (31%)
		Tryp_SPc	389..619	CDD:238113	79/255 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910