Protein Alignment CG3700 and F7

DIOPT Version :10

• Sequence 1: NP_611736.1
• Gene: CG3700 / 37640
• FlyBaseID: FBgn0034796
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: XP_011535776.2
• Gene: F7 / 2155
• HGNCID: 3544
• Length: 495
• Species: Homo sapiens
• Alignment Length: 359
• Identity: 98/359 - (27%)
• Similarity: 149/359 - (41%)
• Gaps: 73/359 - (20%)

  Fly    30 CKELTPS----DCPVIFYNQHLIGAEVKYCDEFN----------------DIVCCPIPLDHQNLK 74
            |..|.||    |..:|..|::  |...:||.:..                |.|.|...:::
Human   164 CSALVPSSPDKDDQLICVNEN--GGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEY---- 222

  Fly    75 PAEQTRPFEKQCKQYNEVRSACQSTPFIVGGTKASGKEFPFMALIGTHRPNKSKSDINWDCGGSV 139
            |..:....||        |:|.:....||||......|.|:..|:..:....        |||::
Human   223 PCGKIPILEK--------RNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQL--------CGGTL 271

  Fly   140 VHPKFVLTAAHCLETDESKAERLDPNFDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYD 204
            ::..:|::||||.  |:.|..|        ..:..|||.|.:....|.  |..||...::...|
Human   272 INTIWVVSAAHCF--DKIKNWR--------NLIAVLGEHDLSEHDGDE--QSRRVAQVIIPSTY- 323

  Fly   205 TEDEEQGFKN-DIALVELDRKAEFNDHVAAVCLPPDSGND-----VQQVTAAGWGFTAD-GVKSS 262
                ..|..| ||||:.|.:.....|||..:|||..:.::     |:....:|||...| |..:.
Human   324 ----VPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATAL 384

  Fly   263 HLLKVNLQRFSDEVCQKRLRFSID----TRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQ 323
            .|:.:|:.|...:.|.::.|...|    |...||||......|:|.|||||| ...|  |.....
Human   385 ELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGP-HATH--YRGTWY 446

  Fly   324 VIGIVSYGLVCGSQGLPSVYTKVHLYTDWIESIV 357
            :.||||:|..|.:.|...|||:|..|.:|::.::
Human   447 LTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLM 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	80/264 (30%)
F7	XP_011535776.2	GLA	36..97	CDD:214503
		EGF_CA	99..135	CDD:238011
		FXa_inhibition	180..216	CDD:464251	6/37 (16%)
		Tryp_SPc	242..478	CDD:238113	80/263 (30%)