DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and Tmprss13

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_006510195.1	Gene:	Tmprss13 / 214531	MGIID:	2682935	Length:	561	Species:	Mus musculus

Alignment Length:	445	Identity:	101/445 - (22%)
Similarity:	159/445 - (35%)	Gaps:	140/445 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LPGIQILLLIASVSVVTEYCDNGTGECKELTPSDCPVIFYNQHLIGAEVKY-------------C 55
            |.|..|||:...:|::..|     |..:..:|....|.|:..|   ..:||             |
Mouse   149 LIGCVILLISLVISLILLY-----GGRETQSPRGTAVYFWRGH---TGIKYKEPLESCPIHAVRC 205

  Fly    56 D-------EFNDIVCCPIPLDHQNLK----PAEQTRPF----------EKQCKQ----------- 88
            |       :.:::.|.....|...||    .:.:..|.          ::.|:|
Mouse   206 DGVVDCKMKSDELGCVRFDWDKSLLKVYSGSSGEWLPVCSSSWNDTDSKRTCQQLGFDSAYRTTE 270

  Fly    89 --------------YNEV------RSACQS----------------TPFIVGGTKASGKEFPFMA 117
                          ||..      ||.|.|                |..||||...|..::|:..
Mouse   271 VAHRDITSSFLLSEYNTTIQESLYRSQCPSRRYVSLQCSHCGLRAMTGRIVGGALTSESKWPWQV 335

  Fly   118 LI---GTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKFVVRLGELD 179
            .:   .||           .|||:::..::|||||||.                  ||.|...|:
Mouse   336 SLHFGTTH-----------ICGGTLIDAQWVLTAAHCF------------------FVTREKLLE 371

  Fly   180 ----YNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEFNDHVAAVCLPPDS 240
                |..|::...:.:...::.::..|..|::::.   .||||:.|.:....:.|:...|||...
Mouse   372 GWKVYAGTSNLHQLPEAASISQIIINGNYTDEQDD---YDIALIRLSKPLTLSAHIHPACLPMHG 433

  Fly   241 G----NDVQQVTAAGWGFTADGVKSSHLLKVNLQRFSDEVCQKRLRF-SIDTRTQFCAGSMSSQA 300
            .    |:...:|..|.....|...|..|.:|.:.....:.|...|.: |..|....|||.:....
Mouse   434 QTFGLNETCWITGFGKTKETDEKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGR 498

  Fly   301 DTCNGDSGGPIFVQ--HPLYPCLKQVIGIVSYGLVCGSQGLPSVYTKVHLYTDWI 353
            |:|.||||||:..:  :..|     :.|:.|:|..||.:..|.|||||.....||
Mouse   499 DSCQGDSGGPLVCEQNNRWY-----LAGVTSWGTGCGQKNKPGVYTKVTEVLPWI 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	71/266 (27%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	69/264 (26%)
Tmprss13	XP_006510195.1	PHA03378	<6..>122	CDD:223065
		LDLa	<204..220	CDD:238060	2/15 (13%)
		SRCR_2	225..314	CDD:373897	12/88 (14%)
		Tryp_SPc	319..548	CDD:214473	69/265 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910