DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and Tmprss15

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_032967.1	Gene:	Tmprss15 / 19146	MGIID:	1197523	Length:	1069	Species:	Mus musculus

Alignment Length:	391	Identity:	100/391 - (25%)
Similarity:	173/391 - (44%)	Gaps:	89/391 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 YCDNGTGE--CKEL---TPSDCPVIFYNQHL---IGAEVKYCDEFNDIVCCPIPLDHQNLK-PAE 77
            :|.:|:.|  |...   |.|:..::.:|.|.   |.....:..:.::.||..:.|...|.. |..
Mouse   712 HCRDGSDEASCVRFLNGTRSNNGLVQFNIHSIWHIACAENWTTQISNEVCHLLGLGSANSSMPIS 776

  Fly    78 QT--RPFEK---------------QCKQYNEVRSAC------------QSTPFIVGGTKASGKEF 113
            .|  .||.:               ||.|.:.:...|            :.:|.||||:.|....:
Mouse   777 STGGGPFVRVNQAPNGSLILTPSLQCSQDSLILLQCNHKSCGEKKVTQKVSPKIVGGSDAQAGAW 841

  Fly   114 PFMALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKFVVRLGEL 178
            |::..: .||   .:|.....||.|:|...::::||||:         ...|.|..::...||..
Mouse   842 PWVVAL-YHR---DRSTDRLLCGASLVSSDWLVSAAHCV---------YRRNLDPTRWTAVLGLH 893

  Fly   179 DYNSTTDDALVQDFRVVN-YVVHPGYDTEDEEQGFKNDIALVELDRKAEFNDHVAAVCLPPDSGN 242
            ..::.|...:|:  |||: .|::|.||...:    .||||::.|:.|..:.|::..:|||.:  |
Mouse   894 MQSNLTSPQVVR--RVVDQIVINPHYDRRRK----VNDIAMMHLEFKVNYTDYIQPICLPEE--N 950

  Fly   243 DV----QQVTAAGWGF-------TADGVKSSHLLKVNLQRFSDEVCQKRL-RFSIDTRTQFCAGS 295
            .:    :..:.||||:       |.|.:|     :.::...|:|.||::| .::| |.:..|||.
Mouse   951 QIFIPGRTCSIAGWGYDKINAGSTVDVLK-----EADVPLISNEKCQQQLPEYNI-TESMICAGY 1009

  Fly   296 MSSQADTCNGDSGGPIFVQHPLYPCLKQ----VIGIVSYGLVCGSQGLPSVYTKVHLYTDWIESI 356
            .....|:|.||||||:.       |.:.    ::|:.|:|:.|.....|.||.:|..:.:||.|.
Mouse  1010 EEGGIDSCQGDSGGPLM-------CQENNRWFLVGVTSFGVQCALPNHPGVYVRVSQFIEWIHSF 1067

  Fly   357 V 357
            :
Mouse  1068 L 1068

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	77/270 (29%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	75/267 (28%)
Tmprss15	NP_032967.1	SEA	53..154	CDD:214554
		LDLa	228..261	CDD:197566
		CUB	270..376	CDD:294042
		MAM	392..549	CDD:279023
		MAM	392..547	CDD:99706
		CUB	569..676	CDD:278839
		LDLa	688..722	CDD:238060	3/9 (33%)
		SR	723..816	CDD:214555	17/92 (18%)
		SRCR	728..819	CDD:278931	17/90 (19%)
		Tryp_SPc	829..1064	CDD:214473	75/268 (28%)
		Tryp_SPc	830..1066	CDD:238113	77/269 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910