Protein Alignment CG3700 and Prss12

DIOPT Version :10

• Sequence 1: NP_611736.1
• Gene: CG3700 / 37640
• FlyBaseID: FBgn0034796
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: NP_032965.1
• Gene: Prss12 / 19142
• MGIID: 1100881
• Length: 761
• Species: Mus musculus
• Alignment Length: 266
• Identity: 79/266 - (29%)
• Similarity: 125/266 - (46%)
• Gaps: 35/266 - (13%)

  Fly   102 IVGGTKASGKEFPFMALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNF 166
            |:||..:....:|:.|.:   |...:..|....||.:::...:|||||||.       :|...|
Mouse   517 IIGGNNSLRGAWPWQASL---RLRSAHGDGRLLCGATLLSSCWVLTAAHCF-------KRYGNN- 570

  Fly   167 DSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVEL----DRKAEF 227
             |..:.||:|  ||::...:...|:..|...|:|..|..:..:.    |||||.|    ::.|..
Mouse   571 -SRSYAVRVG--DYHTLVPEEFEQEIGVQQIVIHRNYRPDRSDY----DIALVRLQGPGEQCARL 628

  Fly   228 NDHVAAVCLPPDSGNDVQQVTAA-----GWGFTADGVKSSHLLKVNLQRFSDEVCQKRLRFSIDT 287
            :.||...|||  ...:..|.||:     |||.|.... |..|.:..:.......|::|.: .:.|
Mouse   629 STHVLPACLP--LWRERPQKTASNCHITGWGDTGRAY-SRTLQQAAVPLLPKRFCKERYK-GLFT 689

  Fly   288 RTQFCAGSM--SSQADTCNGDSGGPIFVQHPLYPCLKQVIGIVSYGLVCGSQGLPSVYTKVHLYT 350
            ....|||::  .::.|:|.||||||:..:.|....:  |.|:.|:|..||.:..|.|||:|..:.
Mouse   690 GRMLCAGNLQEDNRVDSCQGDSGGPLMCEKPDESWV--VYGVTSWGYGCGVKDTPGVYTRVPAFV 752

  Fly   351 DWIESI 356
            .||:|:
Mouse   753 PWIKSV 758

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	78/264 (30%)
Prss12	NP_032965.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	25..87
		KR	83..159	CDD:214527
		SR	166..265	CDD:214555
		SR	273..372	CDD:214555
		SR	386..485	CDD:214555
		Zymogen activation region	505..516
		Tryp_SPc	517..758	CDD:238113	78/264 (30%)