DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and Plat

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_032898.2	Gene:	Plat / 18791	MGIID:	97610	Length:	559	Species:	Mus musculus

Alignment Length:	389	Identity:	105/389 - (26%)
Similarity:	149/389 - (38%)	Gaps:	87/389 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 TEYCDNGTGECKELTPSDC----PVIFYNQHLIGAEVKYCDEFNDIVCC------------PIPL 68
            ||:|  .|..|.:....||    .|.:...|.:......|..:|.||..            .:.|
Mouse   197 TEFC--STPACPKGKSEDCYVGKGVTYRGTHSLTTSQASCLPWNSIVLMGKSYTAWRTNSQALGL 259

  Fly    69 DHQNL--KPAEQTRPFEKQCKQYNEVRSACQSTPF--------------IVGGTKASGKEFPFMA 117
            ...|.  .|....||:....|........|..:|.              |.||........|:.|
Mouse   260 GRHNYCRNPDGDARPWCHVMKDRKLTWEYCDMSPCSTCGLRQYKRPQFRIKGGLYTDITSHPWQA 324

  Fly   118 LIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKFVVRLGELDYNS 182
            .|..  .||......:.|||.::...:||:||||.      .||..||    ...|.||. .|..
Mouse   325 AIFV--KNKRSPGERFLCGGVLISSCWVLSAAHCF------LERFPPN----HLKVVLGR-TYRV 376

  Fly   183 TTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRK----AEFNDHVAAVCLPPDSGN- 242
            ...:. .|.|.:..|:||..:|    :..:.|||||::|..:    |:.:..|...|||..:..
Mouse   377 VPGEE-EQTFEIEKYIVHEEFD----DDTYDNDIALLQLRSQSKQCAQESSSVGTACLPDPNLQL 436

  Fly   243 -DVQQVTAAGWG-------FTADGVKSSHLLKVNLQRFSDEVCQKRLRFS-IDTRTQFCAGSMSS 298
             |..:...:|:|       |.:|.:|.:|     ::.:....|..:..|: ..|....|||...|
Mouse   437 PDWTECELSGYGKHEASSPFFSDRLKEAH-----VRLYPSSRCTSQHLFNKTVTNNMLCAGDTRS 496

  Fly   299 QA-----DTCNGDSGGPIFVQHPLYPCL--KQ--VIGIVSYGLVCGSQGLPSVYTKVHLYTDWI 353
            ..     |.|.||||||:.       |:  ||  :.||:|:||.||.:.:|.|||||..|.|||
Mouse   497 GGNQDLHDACQGDSGGPLV-------CMINKQMTLTGIISWGLGCGQKDVPGVYTKVTNYLDWI 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	84/275 (31%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	82/273 (30%)
Plat	NP_032898.2	FN1	38..80	CDD:214494
		Important for binding to annexin A2. /evidence=ECO:0000250	39..49
		EGF	83..115	CDD:394967
		Kringle	124..205	CDD:395005	4/9 (44%)
		KR	210..295	CDD:238056	16/84 (19%)
		Tryp_SPc	311..556	CDD:238113	83/273 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I4773
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050