DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and svh-1

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_501379.2	Gene:	svh-1 / 182375	WormBaseID:	WBGene00006620	Length:	951	Species:	Caenorhabditis elegans

Alignment Length:	293	Identity:	88/293 - (30%)
Similarity:	141/293 - (48%)	Gaps:	54/293 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 QC-KQYNEV--RSACQS-TPFIVGGTKASGKEFPFMALIGTHRPNKSKSDINWDCGGSVVHPKFV 145
            || .:|.||  |.|.:| ...:|||.:.....||:.|.:      ::|:.....||.|::....:
Worm   692 QCGLRYVEVNARDAAKSRIARVVGGFETVPGAFPWTAAL------RNKATKAHHCGASILDKTHL 750

  Fly   146 LTAAHCLETDESKAERLDPNFDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQ 210
            :|||||.|.||..:          .:.|.:|:.|.|.|  |...|.|.:.....:|.|     :.
Worm   751 ITAAHCFEEDERVS----------SYEVVVGDWDNNQT--DGNEQIFYLQRIHFYPLY-----KD 798

  Fly   211 GFKNDIALVELDRKA-EFNDHVAAVCLPPDSGNDV----QQVTAAGWGFTADGVKSSHLLKVNL- 269
            .|.:|||::|:.... |||::...:|||  |.:.|    :|...:|||  :.|::.:..|:..|
Worm   799 IFSHDIAILEIPYPGIEFNEYAQPICLP--SKDFVYTPGRQCVVSGWG--SMGLRYAERLQAALI 859

  Fly   270 ---QRFSDEVCQKRLRFSIDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQ-----VIG 326
               .|| |.|...:: :|..:|:.||||.:....|:|.||||||       :.|.::     :.|
Worm   860 PIINRF-DCVNSSQI-YSSMSRSAFCAGYLEGGIDSCQGDSGGP-------FACRREDGAFVLAG 915

  Fly   327 IVSYGLVCGSQGLPSVYTKVHLYTDWIESIVWG 359
            ::|:|..|..:..|.:||.|..|..||.:|:.|
Worm   916 VISWGDGCAQKKQPGIYTMVAPYLSWISAIING 948

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	78/267 (29%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	76/264 (29%)
svh-1	NP_501379.2	KR	227..306	CDD:214527
		LDLa	320..355	CDD:238060
		PAN_AP_HGF	373..434	CDD:238532
		LDLa	558..590	CDD:197566
		SRCR_2	599..681	CDD:382996
		Tryp_SPc	713..945	CDD:238113	78/267 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24258
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100