DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and Masp1

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_036015702.1	Gene:	Masp1 / 17174	MGIID:	88492	Length:	746	Species:	Mus musculus

Alignment Length:	418	Identity:	109/418 - (26%)
Similarity:	159/418 - (38%)	Gaps:	113/418 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 ECKEL--------TPSDCPVIFYNQHLIGAEVKY--------CDEF-----------NDIVCC-- 64
            ||.:|        .||.....|.:|.|:..:..|        .|.|           |.|..|
Mouse   305 ECPKLQPPVYGKIEPSQAVYSFKDQVLVSCDTGYKVLKDNEVMDTFQIECLKDGAWSNKIPTCKI 369

  Fly    65 -----PIPLDH--------QNLKPAEQ------TRPFEKQ---------CKQY----NEV--RSA 95
                 |..|.|        .||...:.      .:|:.|.         |..:    |||  ||.
Mouse   370 VDCGAPAGLKHGLVTFSTRNNLTTYKSEIRYSCQQPYYKMLHNTTGVYTCSAHGTWTNEVLKRSL 434

  Fly    96 CQSTPFIVGGTKASGKEFPFMALIGTHRPNKSKSDINW-----------DCGGSVVHPKFVLTAA 149
            ....| :.|..|.|.|:   ::.|...|| ..|..:.|           .||||::...:|||||
Mouse   435 PTCLP-VCGVPKFSRKQ---ISRIFNGRP-AQKGTMPWIAMLSHLNGQPFCGGSLLGSNWVLTAA 494

  Fly   150 HCLETDESKAERLDPN--------FDSPK-FVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDT 205
            |||.      :.|||.        ..||. |.:.:|:.....:.:|.  |...|....:||.|:.
Mouse   495 HCLH------QSLDPEEPTLHSSYLLSPSDFKIIMGKHWRRRSDEDE--QHLHVKRTTLHPLYNP 551

  Fly   206 EDEEQGFKNDIALVELDRKAEFNDHVAAVCLPPDSGNDVQQVTAAGWGFTADGVKSSHLLKVNLQ 270
            ..    |:||:.||||......||.|..||||.....:...|..:|||.........:|:::.:.
Mouse   552 ST----FENDLGLVELSESPRLNDFVMPVCLPEQPSTEGTMVIVSGWGKQFLQRFPENLMEIEIP 612

  Fly   271 RFSDEVCQKR---LRFSIDTRTQFCAGSMSSQADTCNGDSGGPIFV----QHPLYPCLKQVIGIV 328
            ..:.:.||:.   |:..: |:...|||......|.|.||||||:..    :...|     ::|:|
Mouse   613 IVNSDTCQEAYTPLKKKV-TKDMICAGEKEGGKDACAGDSGGPMVTKDAERDQWY-----LVGVV 671

  Fly   329 SYGLVCGSQGLPSVYTKVHLYTDWIESI 356
            |:|..||.:....||:.::...|||:.|
Mouse   672 SWGEDCGKKDRYGVYSYIYPNKDWIQRI 699

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	80/280 (29%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	78/277 (28%)
Masp1	XP_036015702.1	CUB	33..142	CDD:238001
		FXa_inhibition	158..186	CDD:405372
		CUB	190..299	CDD:395345
		PHA02639	<305..>438	CDD:165022	27/132 (20%)
		CCP	306..368	CDD:153056	12/61 (20%)
		Tryp_SPc	454..699	CDD:238113	76/263 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910