DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and Tmprss3

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001157248.1	Gene:	Tmprss3 / 140765	MGIID:	2155445	Length:	475	Species:	Mus musculus

Alignment Length:	274	Identity:	80/274 - (29%)
Similarity:	131/274 - (47%)	Gaps:	49/274 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 SACQS----TPFIVGGTKASGKEFPFMALI---GTHRPNKSKSDINWDCGGSVVHPKFVLTAAHC 151
            |||.:    :|.||||..:|..::|:...:   |.|.           ||||::.|.:::|||||
Mouse   227 SACGTRTGYSPRIVGGNMSSLTQWPWQVSLQFQGYHL-----------CGGSIITPLWIVTAAHC 280

  Fly   152 LETDESKAERLDPNFD--SPK-FVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFK 213
            :             :|  .|| :.|::|.:    :..|:.|....|...:.|..|    :.:...
Mouse   281 V-------------YDLYHPKSWTVQVGLV----SLMDSPVPSHLVEKIIYHSKY----KPKRLG 324

  Fly   214 NDIALVELDRKAEFNDHVAAVCLPPDSGN--DVQQVTAAGWGFTADGVKSSHLLK-VNLQRFSDE 275
            |||||::|.....|::.:..:|||....|  |.:....:|||.|.||..:|.:|. ..:...|::
Mouse   325 NDIALMKLSEPLTFDETIQPICLPNSEENFPDGKLCWTSGWGATEDGGDASPVLNHAAVPLISNK 389

  Fly   276 VCQKR-LRFSIDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQVIGIVSYGLVCGSQGL 339
            :|..| :...|.:.:..|||.:....|:|.||||||:..|...   |.:::|..|:|:.|.....
Mouse   390 ICNHRDVYGGIISPSMLCAGYLKGGVDSCQGDSGGPLVCQERR---LWKLVGATSFGIGCAEVNK 451

  Fly   340 PSVYTKVHLYTDWI 353
            |.|||::..:.|||
Mouse   452 PGVYTRITSFLDWI 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	76/262 (29%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	74/260 (28%)
Tmprss3	NP_001157248.1	LDLa	96..129	CDD:238060
		SRCR_2	134..233	CDD:292133	3/5 (60%)
		Tryp_SPc	238..465	CDD:214473	74/261 (28%)
		Tryp_SPc	239..468	CDD:238113	76/262 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910