DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and AgaP_AGAP001366

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_321777.4	Gene:	AgaP_AGAP001366 / 1281814	VectorBaseID:	AGAP001366	Length:	563	Species:	Anopheles gambiae

Alignment Length:	311	Identity:	76/311 - (24%)
Similarity:	137/311 - (44%)	Gaps:	50/311 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 LDHQNLKPAEQTRPFEKQCKQYNEVRSAC-----QSTPFIVGGTKASGKEFPFMALIGTHRPNKS 127
            |.|::...|.||....|    |.  ...|     ::.|.:..||.:...:||:...:  :|  .:
Mosquito   282 LQHESTPKAGQTHYINK----YE--GDICGTVVPKANPLVTHGTVSERGQFPWHGAL--YR--ST 336

  Fly   128 KSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKFVVRLGELD---YNSTTDDALV 189
            .:::.:.||.:::..:..:|||||:..::|...     .|:...::..|::|   :|...:||.:
Mosquito   337 VTELKYLCGATLISRRASITAAHCVTLEKSSKP-----VDAGSLLLYFGKIDLSKWNGPEEDAQI 396

  Fly   190 QDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEFNDHVAAVCL---PPDSGNDVQQV-TAA 250
            :...:         ..:.:.:.|.||||::.|....::::.|..|||   ..|....:.:: ...
Mosquito   397 RSIHI---------PAQYQHERFFNDIAVLVLKEDIKYSNFVRPVCLWNFDDDYKTLINKIGFVP 452

  Fly   251 GWGFTADGVKSSHLLKVNLQRFSDEVC--QKRLRFS-IDTRTQFCAGSMSSQADTCNGDSGGPIF 312
            |||:...|:.||.|....:...:.|.|  ..|..|| :.:.|.|||| ..:....|||||||.:.
Mosquito   453 GWGYNEHGLVSSRLSFAQMPVVAHETCIWSNRDFFSKVTSDTSFCAG-FKNGTSVCNGDSGGGMV 516

  Fly   313 VQHPLYPCLKQVIGIVSYGLV------CGSQGLPSVYTKVHLYTDWIESIV 357
            .:|.....|:   ||||....      |.|:.. .|:|....:|.||:.::
Mosquito   517 FKHNNLWYLR---GIVSVSAALQDRFHCDSKHY-VVFTDAAKFTSWIKGLM 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	67/269 (25%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	65/266 (24%)
AgaP_AGAP001366	XP_321777.4	GD_N	15..124	CDD:292649
		Tryp_SPc	315..560	CDD:238113	66/267 (25%)
		Tryp_SPc	315..559	CDD:214473	65/266 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910