DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and AgaP_AGAP011669

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_320844.4	Gene:	AgaP_AGAP011669 / 1280970	VectorBaseID:	AGAP011669	Length:	576	Species:	Anopheles gambiae

Alignment Length:	296	Identity:	80/296 - (27%)
Similarity:	121/296 - (40%)	Gaps:	46/296 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 QTRPFEKQ--CKQYNEVRSACQSTPFIVGGTKASGKEFPF-MALIGTHRPNKSKSDINWDCGGSV 139
            |||..|..  |.:...|     |...|..|..|....:|: :||.  ||.:   :...:.||||:
Mosquito    20 QTRGQENHLTCGKRKVV-----SQYLIHNGIDAKAGHWPWHVALF--HRKD---AQYEYACGGSI 74

  Fly   140 VHPKFVLTAAHCLETDESKAERLDPNFDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYD 204
            :....:|||:||:.|....       ....:..|.:|.:..|.:::  ..|...|...:||||:
Mosquito    75 LDENTILTASHCVYTQSGV-------ISISRVSVDVGRIHLNESSE--YTQTHLVREIIVHPGF- 129

  Fly   205 TEDEEQGFKNDIALVELDRKAEFNDHVAAVCL-PPDSGNDV---QQVTAAGWGFTADGVKSSHLL 265
               .:....|||||::|......|.:|..||| ..||..::   :..|..|:|.....|.|..|.
Mosquito   130 ---SKNSIVNDIALIKLSSNITMNKYVQPVCLWTMDSNQELIVGRNGTIVGFGVNEQDVVSEQLK 191

  Fly   266 KVNLQRFSDEVC--QKRLRFSID-TRTQFCAGSMSSQADTCNGDSGGPIF--VQHPLYPCLKQVI 325
            :..:.......|  ..|..|... |...|| |........|||||||.:|  :....:     |.
Mosquito   192 QALIGVVDPLSCIADDRGVFGTHLTSDMFC-GKGQKGVSACNGDSGGGMFFEIGGKWF-----VR 250

  Fly   326 GIVSYGLVCGSQGLPSV----YTKVHLYTDWIESIV 357
            |:||: ...|::...|:    ||.|..|.:||:..:
Mosquito   251 GLVSF-TPLGTEQCDSLKNTAYTDVAKYLEWIKPYI 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	73/267 (27%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	71/264 (27%)
AgaP_AGAP011669	XP_320844.4	Tryp_SPc	41..282	CDD:238113	72/265 (27%)
		Tryp_SPc	43..281	CDD:214473	70/262 (27%)
		Tryp_SPc	330..568	CDD:214473
		Tryp_SPc	330..568	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910