DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and AgaP_AGAP009249

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_320028.4	Gene:	AgaP_AGAP009249 / 1280205	VectorBaseID:	AGAP009249	Length:	776	Species:	Anopheles gambiae

Alignment Length:	264	Identity:	86/264 - (32%)
Similarity:	126/264 - (47%)	Gaps:	53/264 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 RPNKSKSD---------------INWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKFV 172
            ||::..||               :.|:|.|::|...|:||:|.|  |.:.|...:        :|
Mosquito    22 RPHQKMSDFSHLGRIGWTGIDGTVRWNCSGTLVWENFILTSARC--TTDGKYVTI--------YV 76

  Fly   173 VRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEFNDHVAAVCLP 237
            .|.|:||..:.|||...|..::|..:.||.:...|.    .:||||:.|:||...:|.||..||.
Mosquito    77 ARFGDLDLFNATDDQYAQQLKIVEIIRHPEHRHRDR----YHDIALMRLERKVVLHDTVAPACLW 137

  Fly   238 PDSGNDVQQVTAAGWGFTA-DGVKSSHLLKVNLQRFSDEVCQKR------LRFSIDTRTQFCAGS 295
            .|.....::..|.|||.|. ...|:..||||.|...::|.|.:.      ||..:.. .|.|||
Mosquito   138 TDDEIRFKRFEATGWGDTGFAAAKTPILLKVALSPVANEQCNEHYSNLRGLRNGLHA-NQLCAG- 200

  Fly   296 MSSQADTCNGDSGGPIFV-------QHPLYPCLKQVIGIVSYGLVCGSQGLPSVYTKVHLYTDWI 353
             .::.|||.||||||:.|       :.|.      ::|:.|:||.|| ..:|.|||:|..|..||
Mosquito   201 -DARMDTCPGDSGGPLQVKLLHNTRETPF------LVGVTSFGLACG-LSVPGVYTRVAPYVPWI 257

  Fly   354 ESIV 357
            .|::
Mosquito   258 RSVL 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	85/261 (33%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	83/258 (32%)
AgaP_AGAP009249	XP_320028.4	Trypsin	43..257	CDD:278516	79/237 (33%)
		Tryp_SPc	46..260	CDD:238113	81/237 (34%)
		Tryp_SPc	312..552	CDD:304450
		Tryp_SPc	654..>751	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D105391at6960
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920