DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and AgaP_AGAP003960

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_318412.5	Gene:	AgaP_AGAP003960 / 1278781	VectorBaseID:	AGAP003960	Length:	579	Species:	Anopheles gambiae

Alignment Length:	280	Identity:	70/280 - (25%)
Similarity:	120/280 - (42%)	Gaps:	63/280 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 IVGGTKASGKEFPF-MALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDES--KAERLD 163
            |..|.::...::|: :||.     :.::....:.||||::....:|||||||.....  ..|||
Mosquito    39 ITNGLESKEGDWPWHVALF-----HNNRRSFEYACGGSILDQNTILTAAHCLWLSNGLIAKERL- 97

  Fly   164 PNFDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEFN 228
                    :|::|.......:..|  :|......:|||.|:...    ..|||||::|.....|.
Mosquito    98 --------LVQVGRSRLRVASIHA--RDHEAYELIVHPKYNVNQ----IANDIALIKLATDITFT 148

  Fly   229 DHVAAVCLPPDSGNDVQQV-----TAAGWGF-----TADGVKSSHL--------LKVNLQRFSDE 275
            :.|..:|| .:.|:|...:     |..|:|:     ..|.::.:.|        ::.|.:.|:.:
Mosquito   149 NFVQPICL-WNRGDDQSSIVGTLGTVIGFGYDETDNPTDTLREARLPVVSAIDCIQSNREAFATQ 212

  Fly   276 VCQKRLRFSIDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQVIGIVSY------GLVC 334
            :          |...||||..:. ...|||||||.:|..   :..:..:.|:||:      ..:|
Mosquito   213 L----------TSDMFCAGYRNG-TSPCNGDSGGGLFFN---FNNVWYIRGLVSFTKPRQDTTIC 263

  Fly   335 GSQGLPSVYTKVHLYTDWIE 354
            .::.. :|:|.|..|..|||
Mosquito   264 DTKEY-TVFTDVAKYLRWIE 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	70/280 (25%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	67/277 (24%)
AgaP_AGAP003960	XP_318412.5	Tryp_SPc	39..283	CDD:238113	70/280 (25%)
		Tryp_SPc	39..281	CDD:214473	67/277 (24%)
		Tryp_SPc	331..573	CDD:214473
		Tryp_SPc	331..573	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910