DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and AgaP_AGAP008403

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_317049.4	Gene:	AgaP_AGAP008403 / 1277577	VectorBaseID:	AGAP008403	Length:	873	Species:	Anopheles gambiae

Alignment Length:	269	Identity:	95/269 - (35%)
Similarity:	129/269 - (47%)	Gaps:	40/269 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 PFIVGGTKASGKEFPFMALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDP 164
            |....|..|..:||..||.:|....|   ..|:|:||||::...:|||||||...|.:.|    |
Mosquito    15 PLPAFGRPAYLREFAHMAAVGWTGEN---GKIDWNCGGSLIWENYVLTAAHCTADDNNAA----P 72

  Fly   165 NFDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFK---NDIALVELDRKAE 226
            :      |||||:::.:..:||...|..::|..:.||       |..|.   :|:||:.|:|...
Mosquito    73 D------VVRLGDINLDDDSDDKYAQQLKIVEIIRHP-------EHRFSSRYHDLALLRLERNVT 124

  Fly   227 FNDHVAAVCLPPDSGNDVQQVTAAGWGFTADGVKSSHLLKVNLQRFSDEVCQKR-------LRFS 284
            .:|.||..||..|.......:.|.|||.|. ..|:..||||:|.......|.::       ||..
Mosquito   125 LHDTVAPGCLWNDEEIPFPSMEATGWGSTG-FAKTPILLKVSLSLVPKSTCDQQYRKGDRGLRQG 188

  Fly   285 IDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQ---VIGIVSYGLVCGSQGLPSVYTKV 346
            :.. .|.|||.:  :.|||.||||||:  |..|....|.   :|.:.|:|.||| |..|.||.||
Mosquito   189 LQD-YQLCAGDI--KMDTCPGDSGGPL--QMKLLANAKMTPFIIAVTSFGSVCG-QSTPGVYMKV 247

  Fly   347 HLYTDWIES 355
            ..|..||.|
Mosquito   248 SPYIPWIRS 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	94/267 (35%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	91/263 (35%)
AgaP_AGAP008403	XP_317049.4	Tryp_SPc	20..256	CDD:238113	93/262 (35%)
		Tryp_SPc	20..254	CDD:214473	91/260 (35%)
		Tryp_SPc	324..552	CDD:304450
		CLIP	577..617	CDD:295450
		Tryp_SPc	656..872	CDD:304450
		Tryp_SPc	656..869	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D105391at6960
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920