DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and SCRASP2

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_316661.5	Gene:	SCRASP2 / 1277217	VectorBaseID:	AGAP006631	Length:	1343	Species:	Anopheles gambiae

Alignment Length:	318	Identity:	92/318 - (28%)
Similarity:	140/318 - (44%)	Gaps:	43/318 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 EVKYCDEFNDIVCCPIPLDHQNLKPAEQTRPFEKQCKQY--NEVRSA--CQSTPFIVGGTKASGK 111
            :|....|||.   |.|   :.....||.|      |..:  .:||:.  .::|..||||:.::..
Mosquito  1037 DVNLIKEFNS---CDI---NSRYPVAELT------CSNFECGKVRNRKYFKATKRIVGGSTSNPG 1089

  Fly   112 EFPFM-ALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKFVVRL 175
            ::||: |::|      ...::.: |.|.::..::||||:||:....:.....:.|    .:.::|
Mosquito  1090 DWPFIAAILG------GPEEVFY-CAGVLIADQWVLTASHCIGNSPTSHTMRNVN----DWTIQL 1143

  Fly   176 GELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEFNDHVAAVCLPPDS 240
            |.....|.|  ...|..:|...:.||.|:......   |||||.:|..:..|::|:..|||||..
Mosquito  1144 GITRRRSHT--YYGQKVKVKTVIPHPMYNLHIPHD---NDIALFQLATRVAFHEHLLPVCLPPPH 1203

  Fly   241 GNDVQ---QVTAAGWG------FTADGVKSSHLL-KVNLQRFSDEVCQKRLRFSIDTRTQFCAGS 295
            ..::.   ..|..|||      .|.:|......| :||:...|.|:|...|.....|....|||.
Mosquito  1204 IRELPTGINCTVVGWGKREERNSTPNGASYEPTLNEVNVPIVSRELCIDWLETFNVTEGMICAGY 1268

  Fly   296 MSSQADTCNGDSGGPIFVQHPLYPCLKQVIGIVSYGLVCGSQGLPSVYTKVHLYTDWI 353
            .....|.|.||||||:...:|.......|.||||:|:.|....||.||..|..:..||
Mosquito  1269 QEGGRDACQGDSGGPLLCPYPNEKDRWFVGGIVSWGVRCAHPKLPGVYANVPKFIPWI 1326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	79/263 (30%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	77/261 (30%)
SCRASP2	XP_316661.5	Fz	753..857	CDD:279700
		LDLa	889..918	CDD:238060
		LDLa	921..955	CDD:294076
		SRCR_2	956..>1011	CDD:295335
		Tryp_SPc	1079..1326	CDD:214473	77/262 (29%)
		Tryp_SPc	1080..1326	CDD:238113	77/261 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910