DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and AgaP_AGAP008558

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_314667.4	Gene:	AgaP_AGAP008558 / 1275424	VectorBaseID:	AGAP008558	Length:	574	Species:	Anopheles gambiae

Alignment Length:	271	Identity:	74/271 - (27%)
Similarity:	122/271 - (45%)	Gaps:	39/271 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 IVGGTKASGKEFPFMALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDES--KAERLDP 164
            |:||..|...::|:.|.| .||..:|   ..:.|||::::...:||||||::.::.  ..:||.
Mosquito    37 ILGGEDAISGQWPWHAAI-FHRIERS---FMYQCGGAIINQNTILTAAHCVQLNQGVITVDRLS- 96

  Fly   165 NFDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEFND 229
                    |::|.....:.  ::..|:.:....:||..|....    .:|||||::|.....|.:
Mosquito    97 --------VQVGRTYLYAA--ESHTQEHQAERIIVHEEYSAAQ----VRNDIALIKLATDIRFTE 147

  Fly   230 HVAAVCLPPDSGNDVQQV-----TAAGWGFTADGVKSSHLLKVNLQRFSDEVC---QKRLRFSID 286
            :|..|||...:..|:.|:     |..|:|.|..|..:..|....:.....:.|   .:.|...:.
Mosquito   148 YVQPVCLWDRARTDIGQLIGRVGTVIGFGITEIGEVADRLRVAYMPIVDTQTCLESNRNLFGRVL 212

  Fly   287 TRTQFCAGSMSSQADTCNGDSGGPIF--VQHPLYPCLKQVIGIVSY-GLVCGSQGLPSVYTKVHL 348
            ||..|||| ..:....|.|||||.::  :::..|     :.||||: |..|.|..... ::.|..
Mosquito   213 TRNVFCAG-FRNGTTVCGGDSGGGMYFEIENRWY-----IRGIVSFSGQNCQSADFAG-FSDVAT 270

  Fly   349 YTDWIESIVWG 359
            |.|||.....|
Mosquito   271 YLDWINRYTSG 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	73/266 (27%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	71/263 (27%)
AgaP_AGAP008558	XP_314667.4	Tryp_SPc	37..277	CDD:238113	73/265 (28%)
		Tryp_SPc	37..275	CDD:214473	71/263 (27%)
		Tryp_SPc	322..568	CDD:214473
		Tryp_SPc	322..568	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910